Disease: Idiopathic pulmonary hypertension
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ACVRL1 P37023 activin A receptor like type 1 Kinase 9.7E-04 0.493 0.769
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
BMPR1B O00238 bone morphogenetic protein receptor type 1B Kinase 1.00 0.573 0.615
BMPR2 Q13873 bone morphogenetic protein receptor type 2 Kinase 1.00 0.538 0.654
CA9 Q16790 carbonic anhydrase 9 1.3E-09 0.483 0.731
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
EDNRB P24530 endothelin receptor type B G-protein coupled receptor 9.2E-03 0.470 0.846
EIF2AK4 Q9P2K8 eukaryotic translation initiation factor 2 alpha kinase 4 1.2E-15 0.603 0.577
EPAS1 Q99814 endothelial PAS domain protein 1 Transcription factor 0.60 0.454 0.731
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
GDF2 Q9UK05 growth differentiation factor 2 Signaling 2.5E-03 0.529 0.731
HAS2 Q92819 hyaluronan synthase 2 0.99 0.588 0.692
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923
HTR2B P41595 5-hydroxytryptamine receptor 2B G-protein coupled receptor 2.7E-10 0.647 0.538
HYAL2 Q12891 hyaluronidase 2 Enzyme 0.19 0.644 0.577
IL6 P05231 interleukin 6 0.32 0.248 0.962
KCNA5 P22460 potassium voltage-gated channel subfamily A member 5 Ion channel 1.1E-03 0.606 0.500
KCNK3 O14649 potassium two pore domain channel subfamily K member 3 Ion channel 0.90 0.584 0.654