Disease: Proliferative vitreoretinopathy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CAPN5 O15484 calpain 5 Enzyme 2.5E-08 0.663 0.615
TCHP Q9BT92 trichoplein keratin filament binding 1.8E-16 0.570 0.692
YAP1 P46937 Yes associated protein 1 Enzyme modulator 1.00 0.432 0.808
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PLAT P00750 plasminogen activator, tissue type Enzyme 5.7E-05 0.445 0.885
POSTN Q15063 periostin Signaling 1.1E-09 0.428 0.885
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
TIMP3 P35625 TIMP metallopeptidase inhibitor 3 Enzyme modulator 0.63 0.445 0.923
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962