Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
AREG P15514 amphiregulin Signaling 0.35 0.487 0.769
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EZR P15311 ezrin Cellular structure 0.18 0.476 0.808
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
MAP2K1 Q02750 mitogen-activated protein kinase kinase 1 Kinase 0.90 0.439 0.846
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MIB1 Q86YT6 mindbomb E3 ubiquitin protein ligase 1 Enzyme 3.4E-88 0.438 0.769
MIR152 microRNA 152 0.521 0.769
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
RASSF1 Q9NS23 Ras association domain family member 1 Enzyme modulator 4.9E-06 0.420 0.808
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
SRC P12931 SRC proto-oncogene, non-receptor tyrosine kinase Kinase 1.00 0.467 0.885
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923