Disease: Anaplastic astrocytoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AREG P15514 amphiregulin Signaling 0.35 0.487 0.769
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
COX8A P10176 cytochrome c oxidase subunit 8A Enzyme 0.12 0.400 0.846
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EPHA1 P21709 EPH receptor A1 Kinase 1.5E-23 0.544 0.731
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
LATS2 Q9NRM7 large tumor suppressor kinase 2 Kinase 0.99 0.554 0.654
MAP2K1 Q02750 mitogen-activated protein kinase kinase 1 Kinase 0.90 0.439 0.846
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MIB1 Q86YT6 mindbomb E3 ubiquitin protein ligase 1 Enzyme 3.4E-88 0.438 0.769
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PTGDS P41222 prostaglandin D2 synthase Enzyme 5.1E-03 0.503 0.846
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
SMARCE1 Q969G3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 1.00 0.572 0.769