Disease: Factor V Leiden mutation
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADAMTS13 Q76LX8 ADAM metallopeptidase with thrombospondin type 1 motif 13 Enzyme 5.1E-15 0.496 0.769
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
ANXA5 P08758 annexin A5 3.8E-15 0.458 0.769
APOH P02749 apolipoprotein H 1.6E-15 0.563 0.769
CPB2 Q96IY4 carboxypeptidase B2 Enzyme 2.7E-17 0.536 0.846
F10 P00742 coagulation factor X Enzyme 2.3E-06 0.493 0.769
F13A1 P00488 coagulation factor XIII A chain Enzyme 5.3E-08 0.575 0.731
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885
F3 P13726 coagulation factor III, tissue factor Receptor 1.9E-02 0.415 0.846
F5 P12259 coagulation factor V Enzyme 5.9E-15 0.441 0.846
F8 P00451 coagulation factor VIII Enzyme 1.00 0.542 0.769
F9 P00740 coagulation factor IX Enzyme 1.00 0.465 0.885
FGB P02675 fibrinogen beta chain Signaling 0.57 0.584 0.692
GP1BA P07359 glycoprotein Ib platelet subunit alpha Receptor 3.2E-03 0.565 0.692
IL6 P05231 interleukin 6 0.32 0.248 0.962
ITGA2 P17301 integrin subunit alpha 2 6.3E-11 0.522 0.731
ITGB3 P05106 integrin subunit beta 3 Receptor 1.7E-03 0.485 0.846
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
PROC P04070 protein C, inactivator of coagulation factors Va and VIIIa Enzyme 1.9E-05 0.504 0.808
PROS1 P07225 protein S 4.7E-04 0.467 0.846
SERPINC1 P01008 serpin family C member 1 Enzyme modulator 1.00 0.507 0.769