Disease: Depression, Bipolar
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
DISC1 Q9NRI5 DISC1 scaffold protein 1.7E-06 0.548 0.769
DIXDC1 Q155Q3 DIX domain containing 1 Signaling 7.3E-11 0.647 0.385
DRD5 P21918 dopamine receptor D5 G-protein coupled receptor 1.3E-16 0.603 0.423
GAD1 Q99259 glutamate decarboxylase 1 Enzyme 4.6E-02 0.486 0.885
GRIK4 Q16099 glutamate ionotropic receptor kainate type subunit 4 Ion channel 0.11 0.678 0.423
GSK3A P49840 glycogen synthase kinase 3 alpha Kinase 1.00 0.644 0.538
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
HDAC5 Q9UQL6 histone deacetylase 5 Epigenetic regulator 1.00 0.552 0.769
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
INS P01308 insulin 0.30 0.445 0.923
ITIH1 P19827 inter-alpha-trypsin inhibitor heavy chain 1 Enzyme modulator 2.1E-31 0.691 0.462
KMO O15229 kynurenine 3-monooxygenase 4.8E-05 0.674 0.615
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
NCAM1 P13591 neural cell adhesion molecule 1 1.00 0.415 0.885
NDUFV2 P19404 NADH:ubiquinone oxidoreductase core subunit V2 5.6E-03 0.610 0.500
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
RELN P78509 reelin 1.00 0.515 0.731
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923