Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ABCA7 | Q8IZY2 | ATP binding cassette subfamily A member 7 | Transporter | 2.1E-55 | 0.644 | 0.577 |
ACE | P12821 | angiotensin I converting enzyme | Enzyme | 1.0E-37 | 0.328 | 0.923 |
ACHE | P22303 | acetylcholinesterase (Cartwright blood group) | Enzyme | 1.00 | 0.445 | 0.885 |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
AKT2 | P31751 | AKT serine/threonine kinase 2 | Kinase | 0.64 | 0.474 | 0.769 |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
BACE1 | P56817 | beta-secretase 1 | Enzyme | 0.88 | 0.559 | 0.769 |
BCHE | P06276 | butyrylcholinesterase | 1.1E-13 | 0.447 | 0.923 | |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
C5AR1 | P21730 | complement C5a receptor 1 | G-protein coupled receptor | 0.40 | 0.513 | 0.808 |
C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
CAMK4 | Q16566 | calcium/calmodulin dependent protein kinase IV | Kinase | 0.51 | 0.621 | 0.654 |
CASP3 | P42574 | caspase 3 | Enzyme | 0.10 | 0.351 | 0.923 |
CASP6 | P55212 | caspase 6 | Enzyme | 1.3E-04 | 0.610 | 0.615 |
CAT | P04040 | catalase | Enzyme | 1.6E-10 | 0.359 | 0.962 |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
CDK5R1 | Q15078 | cyclin dependent kinase 5 regulatory subunit 1 | Enzyme modulator | 0.91 | 0.529 | 0.808 |
CHRNB2 | P17787 | cholinergic receptor nicotinic beta 2 subunit | Ion channel | 7.3E-04 | 0.617 | 0.308 |
CLU | P10909 | clusterin | 7.8E-05 | 0.426 | 0.885 | |
CNR2 | P34972 | cannabinoid receptor 2 | G-protein coupled receptor | 6.5E-06 | 0.509 | 0.846 |
COX2 | P00403 | cytochrome c oxidase subunit II | Enzyme | 0.352 | 0.962 |