Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ABCB1 | P08183 | ATP binding cassette subfamily B member 1 | Transporter | 1.3E-05 | 0.344 | 0.885 |
SLC22A18 | Q96BI1 | solute carrier family 22 member 18 | Transporter | 6.5E-06 | 0.595 | 0.692 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
NFKB1 | P19838 | nuclear factor kappa B subunit 1 | Transcription factor | 1.00 | 0.396 | 0.923 |
PPARGC1A | Q9UBK2 | PPARG coactivator 1 alpha | Transcription factor | 1.00 | 0.453 | 0.885 |
FOXC1 | Q12948 | forkhead box C1 | Transcription factor | 0.95 | 0.483 | 0.846 |
PER2 | O15055 | period circadian regulator 2 | Transcription factor | 0.71 | 0.488 | 0.846 |
PER1 | O15534 | period circadian regulator 1 | Transcription factor | 2.9E-04 | 0.556 | 0.731 |
PPARGC1B | Q86YN6 | PPARG coactivator 1 beta | Transcription factor | 0.50 | 0.569 | 0.731 |
FOXD3 | Q9UJU5 | forkhead box D3 | Transcription factor | 0.58 | 0.587 | 0.692 |
AATF | Q9NY61 | apoptosis antagonizing transcription factor | Transcription factor | 2.6E-12 | 0.641 | 0.731 |
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
CXCL10 | P02778 | C-X-C motif chemokine ligand 10 | Signaling | 0.37 | 0.378 | 0.885 |
PRL | P01236 | prolactin | Signaling | 2.9E-07 | 0.406 | 0.885 |
ANGPT2 | O15123 | angiopoietin 2 | Signaling | 0.83 | 0.410 | 0.846 |
ANGPT1 | Q15389 | angiopoietin 1 | Signaling | 0.95 | 0.446 | 0.808 |
MDM2 | Q00987 | MDM2 proto-oncogene | Nucleic acid binding | 1.00 | 0.362 | 0.846 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
MSH6 | P52701 | mutS homolog 6 | Nucleic acid binding | 3.7E-05 | 0.462 | 0.731 |
NBN | O60934 | nibrin | Nucleic acid binding | 2.2E-16 | 0.467 | 0.808 |
MDM4 | O15151 | MDM4 regulator of p53 | Nucleic acid binding | 1.00 | 0.461 | 0.808 |