Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
EDN1 | P05305 | endothelin 1 | Signaling | 0.46 | 0.380 | 0.846 |
MMP2 | P08253 | matrix metallopeptidase 2 | Enzyme | 0.84 | 0.333 | 0.923 |
FGFR2 | P21802 | fibroblast growth factor receptor 2 | Kinase | 1.00 | 0.380 | 0.808 |
MECP2 | P51608 | methyl-CpG binding protein 2 | Epigenetic regulator | 0.89 | 0.414 | 0.846 |
FGFR1 | P11362 | fibroblast growth factor receptor 1 | Kinase | 1.00 | 0.362 | 0.885 |
IDH2 | P48735 | isocitrate dehydrogenase (NADP(+)) 2 | 0.88 | 0.434 | 0.808 | |
NOTCH1 | P46531 | notch receptor 1 | 1.00 | 0.369 | 0.885 | |
COL2A1 | P02458 | collagen type II alpha 1 chain | 1.00 | 0.444 | 0.846 | |
TGFBR2 | P37173 | transforming growth factor beta receptor 2 | Kinase | 0.13 | 0.413 | 0.846 |
ACTG1 | P63261 | actin gamma 1 | Cellular structure | 4.8E-03 | 0.477 | 0.846 |
TP63 | Q9H3D4 | tumor protein p63 | Transcription factor | 1.00 | 0.362 | 0.769 |
PAX6 | P26367 | paired box 6 | 1.00 | 0.450 | 0.769 | |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
SMAD4 | Q13485 | SMAD family member 4 | Transcription factor | 1.00 | 0.401 | 0.808 |
TCF4 | P15884 | transcription factor 4 | Transcription factor | 1.00 | 0.464 | 0.846 |
LMNA | P02545 | lamin A/C | 1.00 | 0.384 | 0.885 | |
PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
RHOA | P61586 | ras homolog family member A | Enzyme modulator | 0.60 | 0.502 | 0.808 |
DNMT3A | Q9Y6K1 | DNA methyltransferase 3 alpha | 7.4E-39 | 0.445 | 0.846 | |
EP300 | Q09472 | E1A binding protein p300 | 1.00 | 0.459 | 0.846 | |
PDGFRA | P16234 | platelet derived growth factor receptor alpha | Kinase | 1.00 | 0.415 | 0.808 |
LETM1 | O95202 | leucine zipper and EF-hand containing transmembrane protein 1 | Transporter | 1.2E-06 | 0.545 | 0.692 |