Disease: Metabolic Syndrome X
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
IL6 P05231 interleukin 6 0.32 0.248 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
HPGDS O60760 hematopoietic prostaglandin D synthase 1.8E-06 0.388 0.923
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885