Disease: Glaucoma, Open-Angle
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ADRB2 P07550 adrenoceptor beta 2 G-protein coupled receptor 0.53 0.442 0.923
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
AKR1B1 P15121 aldo-keto reductase family 1 member B Enzyme 2.0E-05 0.491 0.885
ANGPT1 Q15389 angiopoietin 1 Signaling 0.95 0.446 0.808
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ARHGEF12 Q9NZN5 Rho guanine nucleotide exchange factor 12 1.00 0.686 0.385
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
CAV2 P51636 caveolin 2 Enzyme modulator 2.7E-02 0.575 0.692
CCHCR1 Q8TD31 coiled-coil alpha-helical rod protein 1 1.0E-16 0.505 0.808
CD38 P28907 CD38 molecule Enzyme 2.3E-06 0.407 0.885
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769
CDKN2B-AS1 CDKN2B antisense RNA 1 0.491 0.769
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CYP1B1 Q16678 cytochrome P450 family 1 subfamily B member 1 Enzyme 2.2E-05 0.457 0.769
DCLRE1B Q9H816 DNA cross-link repair 1B 0.54 0.716 0.577
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
FDXR P22570 ferredoxin reductase Enzyme 1.1E-06 0.566 0.808
FMNL2 Q96PY5 formin like 2 0.99 0.729 0.231
FNDC3B Q53EP0 fibronectin type III domain containing 3B 1.00 0.674 0.385
FOXC1 Q12948 forkhead box C1 Transcription factor 0.95 0.483 0.846