Disease: Prion Diseases
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
CLU P10909 clusterin 7.8E-05 0.426 0.885
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
AQP1 P29972 aquaporin 1 (Colton blood group) Ion channel 2.6E-07 0.467 0.885
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
RELN P78509 reelin 1.00 0.515 0.731
CR1 P17927 complement C3b/C4b receptor 1 (Knops blood group) 1.6E-35 0.533 0.808
MINDY4 Q4G0A6 MINDY lysine 48 deubiquitinase 4 3.2E-19 0.538 0.731
CD2AP Q9Y5K6 CD2 associated protein 0.23 0.558 0.731
TOMM40 O96008 translocase of outer mitochondrial membrane 40 Transporter 0.99 0.590 0.538
ABCA7 Q8IZY2 ATP binding cassette subfamily A member 7 Transporter 2.1E-55 0.644 0.577