Disease: Mental deterioration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABI3 Q9P2A4 ABI family member 3 Enzyme modulator 5.0E-05 0.716 0.231
APBB1 O00213 amyloid beta precursor protein binding family B member 1 0.97 0.722 0.346
VSNL1 P62760 visinin like 1 0.46 0.631 0.423
CYP46A1 Q9Y6A2 cytochrome P450 family 46 subfamily A member 1 Enzyme 0.99 0.659 0.500
PICALM Q13492 phosphatidylinositol binding clathrin assembly protein Transporter 1.00 0.592 0.538
AGPS O00116 alkylglycerone phosphate synthase 1.00 0.670 0.538
TOMM40 O96008 translocase of outer mitochondrial membrane 40 Transporter 0.99 0.590 0.538
IDE P14735 insulin degrading enzyme Enzyme 6.6E-03 0.604 0.577
ABCA7 Q8IZY2 ATP binding cassette subfamily A member 7 Transporter 2.1E-55 0.644 0.577
HTT P42858 huntingtin 1.00 0.548 0.654
PSEN2 P49810 presenilin 2 Enzyme 5.4E-04 0.550 0.654
BIN1 O00499 bridging integrator 1 0.78 0.550 0.692
SORL1 Q92673 sortilin related receptor 1 Transporter 7.7E-11 0.582 0.692
INPP5D Q92835 inositol polyphosphate-5-phosphatase D 0.97 0.558 0.731
A2M P01023 alpha-2-macroglobulin Enzyme modulator 4.5E-11 0.529 0.769
CD33 P20138 CD33 molecule Receptor 5.7E-07 0.524 0.769
NECTIN2 Q92692 nectin cell adhesion molecule 2 0.97 0.575 0.769
ARC Q7LC44 activity regulated cytoskeleton associated protein 0.59 0.573 0.769
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808
TPP1 O14773 tripeptidyl peptidase 1 Enzyme 6.3E-07 0.551 0.808
CR1 P17927 complement C3b/C4b receptor 1 (Knops blood group) 1.6E-35 0.533 0.808
CST3 P01034 cystatin C 3.9E-03 0.436 0.808