Disease: Dementia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846
AGPS O00116 alkylglycerone phosphate synthase 1.00 0.670 0.538
A2M P01023 alpha-2-macroglobulin Enzyme modulator 4.5E-11 0.529 0.769
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ANXA1 P04083 annexin A1 1.2E-07 0.442 0.885
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808
APOC1 P02654 apolipoprotein C1 0.22 0.581 0.577
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ABCA7 Q8IZY2 ATP binding cassette subfamily A member 7 Transporter 2.1E-55 0.644 0.577
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769
BACE2 Q9Y5Z0 beta-secretase 2 Enzyme 6.8E-03 0.628 0.615
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
BIN1 O00499 bridging integrator 1 0.78 0.550 0.692
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CTSF Q9UBX1 cathepsin F Enzyme 1.9E-13 0.716 0.462
CD2AP Q9Y5K6 CD2 associated protein 0.23 0.558 0.731
CHRNA7 P36544 Q494W8 cholinergic receptor nicotinic alpha 7 subunit Ion channel 4.2E-04 0.532 0.654
CHRNB2 P17787 cholinergic receptor nicotinic beta 2 subunit Ion channel 7.3E-04 0.617 0.308
CLU P10909 clusterin 7.8E-05 0.426 0.885