Disease: Hypertrophic Cardiomyopathy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
RPL36A-HNRNPH2 RPL36A-HNRNPH2 readthrough 0.36 0.861 0.154
MYL2 P10916 myosin light chain 2 Calcium-binding protein 2.7E-08 0.601 0.615
MYL3 P08590 myosin light chain 3 Calcium-binding protein 8.8E-02 0.695 0.308
TNNC1 P63316 troponin C1, slow skeletal and cardiac type Calcium-binding protein 0.68 0.647 0.462
MYL9 P24844 myosin light chain 9 Calcium-binding protein 2.0E-02 0.653 0.423
MYL12A O14950 P19105 myosin light chain 12A Calcium-binding protein 5.1E-04 0.682 0.462
MYL12B O14950 P19105 myosin light chain 12B Calcium-binding protein 0.11 0.691 0.462
ACTA2 P62736 actin alpha 2, smooth muscle Cellular structure 0.93 0.508 0.846
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
ACTC1 P68032 actin alpha cardiac muscle 1 Cellular structure 0.74 0.610 0.538
TNNI3 P19429 troponin I3, cardiac type Cellular structure 9.6E-02 0.520 0.769
TNNT2 P45379 troponin T2, cardiac type Cellular structure 2.0E-03 0.601 0.423
TPM1 P09493 tropomyosin 1 Cellular structure 1.0E-03 0.560 0.615
MYOZ2 Q9NPC6 myozenin 2 Cellular structure 1.6E-03 0.716 0.308
XIRP1 Q702N8 xin actin binding repeat containing 1 Cellular structure 2.3E-30 0.780 0.269
CAPN2 P17655 calpain 2 Enzyme 3.5E-22 0.590 0.692
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
FXN Q16595 frataxin Enzyme 0.34 0.510 0.654
PEPD P12955 peptidase D Enzyme 1.5E-14 0.621 0.769
NMNAT2 Q9BZQ4 nicotinamide nucleotide adenylyltransferase 2 Enzyme 0.99 0.670 0.500
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
CAV3 P56539 caveolin 3 Enzyme modulator 5.5E-03 0.564 0.692
PRKAG2 Q9UGJ0 protein kinase AMP-activated non-catalytic subunit gamma 2 Enzyme modulator 1.00 0.582 0.654