| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
| PALB2 | Q86YC2 | partner and localizer of BRCA2 | 3.0E-19 | 0.485 | 0.769 | |
| CHEK2 | O96017 | checkpoint kinase 2 | Kinase | 1.2E-24 | 0.460 | 0.808 |
| ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
| APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
| PMS2 | P54278 | PMS1 homolog 2, mismatch repair system component | Nucleic acid binding | 4.5E-27 | 0.484 | 0.808 |
| BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
| MUTYH | Q9UIF7 | mutY DNA glycosylase | Enzyme | 1.3E-18 | 0.521 | 0.769 |
| BRIP1 | Q9BX63 | BRCA1 interacting protein C-terminal helicase 1 | Enzyme | 6.2E-17 | 0.507 | 0.731 |
| NBN | O60934 | nibrin | Nucleic acid binding | 2.2E-16 | 0.467 | 0.808 |
| HOXB13 | Q92826 | homeobox B13 | 3.7E-08 | 0.573 | 0.462 |