Disease: Paroxysmal familial ventricular fibrillation
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846
CALM2 P0DP23 P0DP24 P0DP25 calmodulin 2 Calcium-binding protein 0.92 0.472 0.808
DSG2 Q14126 desmoglein 2 Cell adhesion 2.8E-10 0.601 0.692
HCN4 Q9Y3Q4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 Ion channel 1.00 0.617 0.269
KCNE5 Q9UJ90 potassium voltage-gated channel subfamily E regulatory subunit 5 0.12 0.666 0.500
KCNQ1 P51787 potassium voltage-gated channel subfamily Q member 1 Ion channel 4.5E-08 0.485 0.769
PKP2 Q99959 plakophilin 2 Cellular structure 3.1E-18 0.606 0.538
RANGRF Q9HD47 RAN guanine nucleotide release factor 2.4E-05 0.751 0.231
RYR2 Q92736 ryanodine receptor 2 Ion channel 1.00 0.539 0.615
SCN3B Q9NY72 sodium voltage-gated channel beta subunit 3 Ion channel 5.1E-02 0.686 0.269
SCN5A Q14524 sodium voltage-gated channel alpha subunit 5 Ion channel 0.91 0.513 0.654