Disease: Cocaine-Related Disorders
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CAMK2A Q9UQM7 calcium/calmodulin dependent protein kinase II alpha Kinase 1.00 0.612 0.538
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CREB1 P16220 cAMP responsive element binding protein 1 1.00 0.463 0.885
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CRHBP P24387 corticotropin releasing hormone binding protein Signaling 0.21 0.659 0.500
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
GAD1 Q99259 glutamate decarboxylase 1 Enzyme 4.6E-02 0.486 0.885
GAD2 Q05329 glutamate decarboxylase 2 Enzyme 0.75 0.529 0.731
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885
GRIA2 P42262 glutamate ionotropic receptor AMPA type subunit 2 Ion channel 1.00 0.573 0.692
GRM5 P41594 glutamate metabotropic receptor 5 G-protein coupled receptor 1.00 0.525 0.846
HDAC5 Q9UQL6 histone deacetylase 5 Epigenetic regulator 1.00 0.552 0.769
HOMER1 Q86YM7 homer scaffold protein 1 1.00 0.636 0.538
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577