Disease: Turcot syndrome (disorder)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MLH3 Q9UHC1 mutL homolog 3 Nucleic acid binding 4.9E-08 0.582 0.538
BAAT Q14032 bile acid-CoA:amino acid N-acyltransferase 7.9E-08 0.578 0.654
PMS1 P54277 PMS1 homolog 1, mismatch repair system component Nucleic acid binding 1.3E-17 0.569 0.654
FBXO11 Q86XK2 F-box protein 11 Enzyme 1.00 0.604 0.692
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
IGF2R P11717 insulin like growth factor 2 receptor Receptor 1.00 0.518 0.731
POLE Q07864 DNA polymerase epsilon, catalytic subunit 8.0E-27 0.526 0.731
CDX2 Q99626 caudal type homeobox 2 Transcription factor 0.53 0.458 0.769
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769
FAP Q12884 fibroblast activation protein alpha Enzyme 1.9E-28 0.496 0.808
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
MRC1 P22897 mannose receptor C-type 1 0.94 0.413 0.846
PDCD1 Q15116 programmed cell death 1 0.42 0.402 0.846
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846
MIR148A microRNA 148a 0.506 0.846
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885