Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
AR | P10275 | androgen receptor | Nuclear receptor | 0.99 | 0.351 | 0.846 |
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
BCL2L11 | O43521 | BCL2 like 11 | 0.89 | 0.510 | 0.731 | |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
BRIP1 | Q9BX63 | BRCA1 interacting protein C-terminal helicase 1 | Enzyme | 6.2E-17 | 0.507 | 0.731 |
CDH1 | P12830 | cadherin 1 | 0.15 | 0.401 | 0.808 | |
CDKN1B | P46527 | cyclin dependent kinase inhibitor 1B | 0.62 | 0.409 | 0.769 | |
CHEK2 | O96017 | checkpoint kinase 2 | Kinase | 1.2E-24 | 0.460 | 0.808 |
CYP17A1 | P05093 | cytochrome P450 family 17 subfamily A member 1 | 2.6E-04 | 0.462 | 0.769 | |
CYP19A1 | P11511 | cytochrome P450 family 19 subfamily A member 1 | Enzyme | 1.7E-05 | 0.410 | 0.885 |
CYP1A1 | P04798 | cytochrome P450 family 1 subfamily A member 1 | Enzyme | 1.1E-17 | 0.436 | 0.846 |
CYP1B1 | Q16678 | cytochrome P450 family 1 subfamily B member 1 | Enzyme | 2.2E-05 | 0.457 | 0.769 |
KLK3 | P07288 | kallikrein related peptidase 3 | Enzyme | 4.4E-06 | 0.443 | 0.885 |
MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
NBN | O60934 | nibrin | Nucleic acid binding | 2.2E-16 | 0.467 | 0.808 |
PALB2 | Q86YC2 | partner and localizer of BRCA2 | 3.0E-19 | 0.485 | 0.769 | |
PPM1D | O15297 | protein phosphatase, Mg2+/Mn2+ dependent 1D | Enzyme | 2.2E-11 | 0.513 | 0.808 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
VDR | P11473 | vitamin D receptor | Nuclear receptor | 1.7E-05 | 0.352 | 0.885 |