Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923
CDH1 P12830 cadherin 1 0.15 0.401 0.808
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
KLF6 Q99612 Kruppel like factor 6 Nucleic acid binding 0.98 0.501 0.846
LZTS1 Q9Y250 leucine zipper tumor suppressor 1 0.95 0.633 0.385
MAD1L1 Q9Y6D9 mitotic arrest deficient 1 like 1 6.8E-16 0.570 0.731
MSR1 P21757 macrophage scavenger receptor 1 Enzyme 2.2E-20 0.553 0.654
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
PLAG1 Q6DJT9 PLAG1 zinc finger Transcription factor 1.00 0.493 0.808
PPM1D O15297 protein phosphatase, Mg2+/Mn2+ dependent 1D Enzyme 2.2E-11 0.513 0.808
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962