Disease: Metastatic castration-resistant prostate cancer
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CYP17A1 P05093 cytochrome P450 family 17 subfamily A member 1 2.6E-04 0.462 0.769
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
ERG P11308 ETS transcription factor ERG Transcription factor 0.96 0.453 0.808
HOXB13 Q92826 homeobox B13 3.7E-08 0.573 0.462
KLK3 P07288 kallikrein related peptidase 3 Enzyme 4.4E-06 0.443 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
NPEPPS P55786 aminopeptidase puromycin sensitive Enzyme 1.00 0.519 0.808
PLAG1 Q6DJT9 PLAG1 zinc finger Transcription factor 1.00 0.493 0.808
PROS1 P07225 protein S 4.7E-04 0.467 0.846
PSAT1 Q9Y617 phosphoserine aminotransferase 1 1.1E-08 0.478 0.846
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885