Disease: Prion Diseases
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846
APCS P02743 amyloid P component, serum 3.2E-02 0.531 0.808
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
CR1 P17927 complement C3b/C4b receptor 1 (Knops blood group) 1.6E-35 0.533 0.808
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
MIR342 microRNA 342 0.547 0.769
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
GSN P06396 gelsolin Cellular structure 3.9E-11 0.475 0.885
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
SERPINA3 P01011 serpin family A member 3 Enzyme modulator 8.8E-14 0.486 0.846
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
IAPP P10997 islet amyloid polypeptide Signaling 3.2E-03 0.507 0.808
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885