Disease: Midface retrusion
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
BMP4 P12644 bone morphogenetic protein 4 Signaling 0.96 0.422 0.808
CANT1 Q8WVQ1 calcium activated nucleotidase 1 2.5E-06 0.619 0.731
CDKN1C P49918 cyclin dependent kinase inhibitor 1C 0.82 0.456 0.846
CILK1 Q9UPZ9 ciliogenesis associated kinase 1 Kinase 1.3E-05 0.545 0.808
COL11A1 P12107 collagen type XI alpha 1 chain 1.00 0.495 0.846
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
GLI2 P10070 GLI family zinc finger 2 0.97 0.446 0.846
GMNN O75496 geminin DNA replication inhibitor 0.11 0.554 0.808
HDAC4 P56524 histone deacetylase 4 Epigenetic regulator 1.00 0.484 0.885
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
KAT6B Q8WYB5 lysine acetyltransferase 6B Enzyme 1.00 0.525 0.731
NECTIN1 Q15223 nectin cell adhesion molecule 1 6.1E-02 0.523 0.808
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846
ROR2 Q01974 receptor tyrosine kinase like orphan receptor 2 Kinase 1.2E-04 0.498 0.731
RUNX2 Q13950 RUNX family transcription factor 2 Transcription factor 0.95 0.437 0.846
SATB2 Q9UPW6 SATB homeobox 2 Transcription factor 1.00 0.503 0.769
SOX11 P35716 SRY-box transcription factor 11 Transcription factor 0.86 0.494 0.808
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808
TCOF1 Q13428 treacle ribosome biogenesis factor 1 0.95 0.550 0.808
TMCO1 Q9UM00 transmembrane and coiled-coil domains 1 9.4E-10 0.588 0.654
TWIST1 Q15672 twist family bHLH transcription factor 1 Transcription factor 0.34 0.397 0.846