| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
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0.070 | GeneticVariation | BEFREE | SNPs rs10994336 and rs9804190 in ANK3 and rs1006737 in CACNA1C have emerged as the most highly replicated SNPs significantly associated with BD. | 29684488 | 2018 |
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0.070 | GeneticVariation | BEFREE | These findings support effects of rs9804190 on frontotemporal WM in adolescents and adults with BD and suggest a mechanism contributing to WM pathology in BD. | 27240527 | 2017 |
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0.070 | GeneticVariation | BEFREE | We examined the effect of BD-risk polymorphisms at rs10994336 and rs9804190 on the working memory (WM) circuit using functional magnetic resonance imaging (fMRI) data obtained from euthymic patients with BD (n = 41), their psychiatrically healthy first-degree relatives (n = 25) and unrelated individuals without personal or family history of psychiatric disorders (n = 46) while performing the N-back task. | 25711502 | 2015 |
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0.070 | GeneticVariation | BEFREE | Initially, we focused on rs9804190-a SNP previously reported to be associated with bipolar disorder, schizophrenia, and ankyrin G expression in brain. | 23796624 | 2013 |
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0.070 | GeneticVariation | BEFREE | We found no association of rs9804190 and rs10994336 with bipolar disorder, unipolar depression or schizophrenia. | 21702894 | 2011 |
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0.070 | GeneticVariation | BEFREE | Combining our Scandinavian samples with an Icelandic sample (N = 435 BD cases, 651 SZ cases, and 11,491 healthy controls), we found rs10994336 and rs9804190 to be nominally significantly associated with BD in this combined Nordic BD sample (N = 1,289/14,105). | 21972176 | 2011 |
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0.070 | GeneticVariation | BEFREE | We first reported association between BD and the ANK3 marker rs9804190 in a genome-wide association study (GWAS) of two independent samples (Baum et al., 2008). | 19088739 | 2009 |