Gene: TP53 ×
Source: BEFREE ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1131691014
rs1131691014
TP53
0.100 GeneticVariation BEFREE Unexpectedly no significant association was found between this potential marker TP53 Arg72Pro and CRC (p > 0.05). 25537146

2015
dbSNP: rs878854066
rs878854066
TP53
0.100 GeneticVariation BEFREE Unexpectedly no significant association was found between this potential marker TP53 Arg72Pro and CRC (p > 0.05). 25537146

2015
dbSNP: rs1042522
rs1042522
TP53
0.100 GeneticVariation BEFREE The SNP rs4938723 and diabetes mellitus (DM) together were associated with an increased CRC risk, but the SNP TP53 Arg72Pro CC with DM showed a protective effect against CRC. 24337371

2014
dbSNP: rs1131691014
rs1131691014
TP53
0.100 GeneticVariation BEFREE The SNP rs4938723 and diabetes mellitus (DM) together were associated with an increased CRC risk, but the SNP TP53 Arg72Pro CC with DM showed a protective effect against CRC. 24337371

2014
dbSNP: rs878854066
rs878854066
TP53
0.100 GeneticVariation BEFREE The SNP rs4938723 and diabetes mellitus (DM) together were associated with an increased CRC risk, but the SNP TP53 Arg72Pro CC with DM showed a protective effect against CRC. 24337371

2014
dbSNP: rs1042522
rs1042522
TP53
0.100 GeneticVariation BEFREE We aimed to investigate the association between miR-34b/c rs4938723 and TP53 Arg72Pro polymorphisms and the risk of CRC. 23183747

2013
dbSNP: rs1131691014
rs1131691014
TP53
0.100 GeneticVariation BEFREE We aimed to investigate the association between miR-34b/c rs4938723 and TP53 Arg72Pro polymorphisms and the risk of CRC. 23183747

2013
dbSNP: rs878854066
rs878854066
TP53
0.100 GeneticVariation BEFREE We aimed to investigate the association between miR-34b/c rs4938723 and TP53 Arg72Pro polymorphisms and the risk of CRC. 23183747

2013
dbSNP: rs587780071
rs587780071
TP53
0.010 GeneticVariation BEFREE Our study is the first study that investigates the relationship among variants of CDKN2 p16 540 C>G, 580 C>T, and MDM2 SNP309 T>G risk of CRC and the development and progression in the Turkish population. 23777425

2013
dbSNP: rs1042522
rs1042522
TP53
0.100 GeneticVariation BEFREE The gene-gene interaction between TP53 Arg72Pro and MDM2 T309G may interact in carcinogenesis of CRC in Chinese, especially in smokers, and this kind of interaction is associated with onset age of CRC. 22744426

2012
dbSNP: rs1131691014
rs1131691014
TP53
0.100 GeneticVariation BEFREE The gene-gene interaction between TP53 Arg72Pro and MDM2 T309G may interact in carcinogenesis of CRC in Chinese, especially in smokers, and this kind of interaction is associated with onset age of CRC. 22744426

2012
dbSNP: rs878854066
rs878854066
TP53
0.100 GeneticVariation BEFREE The gene-gene interaction between TP53 Arg72Pro and MDM2 T309G may interact in carcinogenesis of CRC in Chinese, especially in smokers, and this kind of interaction is associated with onset age of CRC. 22744426

2012
dbSNP: rs1042522
rs1042522
TP53
0.100 GeneticVariation BEFREE Association of Arg72Pro of P53 polymorphism with colorectal cancer susceptibility risk in Malaysian population. 22393962

2011
dbSNP: rs1042522
rs1042522
TP53
0.100 GeneticVariation BEFREE TP53 R72P and MDM2 SNP309 polymorphisms and colorectal cancer risk: the Fukuoka Colorectal Cancer Study. 21051533

2011
dbSNP: rs1131691014
rs1131691014
TP53
0.100 GeneticVariation BEFREE Association of Arg72Pro of P53 polymorphism with colorectal cancer susceptibility risk in Malaysian population. 22393962

2011
dbSNP: rs1131691014
rs1131691014
TP53
0.100 GeneticVariation BEFREE TP53 R72P and MDM2 SNP309 polymorphisms and colorectal cancer risk: the Fukuoka Colorectal Cancer Study. 21051533

2011
dbSNP: rs878854066
rs878854066
TP53
0.100 GeneticVariation BEFREE TP53 R72P and MDM2 SNP309 polymorphisms and colorectal cancer risk: the Fukuoka Colorectal Cancer Study. 21051533

2011
dbSNP: rs878854066
rs878854066
TP53
0.100 GeneticVariation BEFREE Association of Arg72Pro of P53 polymorphism with colorectal cancer susceptibility risk in Malaysian population. 22393962

2011
dbSNP: rs1042522
rs1042522
TP53
0.100 GeneticVariation BEFREE We did not identify an association between TP53 rs1042522 and colorectal cancer. 20615891

2010
dbSNP: rs1042522
rs1042522
TP53
0.100 GeneticVariation BEFREE We conclude that Arg72Pro SNP is associated with susceptibility to developing CRC in this ethnic Kashmiri population. 20449797

2010
dbSNP: rs1042522
rs1042522
TP53
0.100 GeneticVariation BEFREE Our data suggest that R72P variant seems to be associated with high risk for development of CRC but carries low risk for development of UC. 20309662

2010
dbSNP: rs1131691014
rs1131691014
TP53
0.100 GeneticVariation BEFREE We conclude that Arg72Pro SNP is associated with susceptibility to developing CRC in this ethnic Kashmiri population. 20449797

2010
dbSNP: rs1131691014
rs1131691014
TP53
0.100 GeneticVariation BEFREE We searched multiple electronic databases to identify studies investigating the association between the Arg72Pro polymorphism and colorectal cancer. 20615891

2010
dbSNP: rs1131691014
rs1131691014
TP53
0.100 GeneticVariation BEFREE Our data suggest that R72P variant seems to be associated with high risk for development of CRC but carries low risk for development of UC. 20309662

2010
dbSNP: rs878854066
rs878854066
TP53
0.100 GeneticVariation BEFREE We searched multiple electronic databases to identify studies investigating the association between the Arg72Pro polymorphism and colorectal cancer. 20615891

2010