Gene: TCF7L2 ×
Source: CURATED ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Genetics of Type 2 Diabetes in U.S. Hispanic/Latino Individuals: Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). 28254843

2017
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. 19734900

2009
dbSNP: rs7903146
rs7903146
TCF7L2
A 0.900 GeneticVariation GWASCAT A genome-wide association study of the metabolic syndrome in Indian Asian men. 20694148

2010
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. 30054458

2018
dbSNP: rs7903146
rs7903146
TCF7L2
0.900 GeneticVariation GWASCAT A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. 17460697

2007
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes. 25102180

2014
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922

2012
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 24509480

2014
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India. 23300278

2013
dbSNP: rs4506565
rs4506565
TCF7L2
T 0.870 GeneticVariation GWASCAT Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. 17554300

2007
dbSNP: rs117229942
rs117229942
TCF7L2
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
dbSNP: rs117229942
rs117229942
TCF7L2
C 0.700 GeneticVariation GWASCAT Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. 30054458

2018
dbSNP: rs34872471
rs34872471
TCF7L2
C 0.700 GeneticVariation GWASCAT Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility. 27189021

2016
dbSNP: rs34872471
rs34872471
TCF7L2
C 0.700 GeneticVariation GWASCAT T2DM GWAS in the Lebanese population confirms the role of TCF7L2 and CDKAL1 in disease susceptibility. 25483131

2014
dbSNP: rs34872471
rs34872471
TCF7L2
C 0.700 GeneticVariation GWASCAT Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes. 29358691

2018
dbSNP: rs34872471
rs34872471
TCF7L2
C 0.700 GeneticVariation GWASCAT Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes. 26818947

2016
dbSNP: rs386418874
rs386418874
TCF7L2
0.700 GeneticVariation GWASCAT ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response. 31324766

2019
dbSNP: rs4918796
rs4918796
TCF7L2
C 0.700 GeneticVariation GWASCAT Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. 30054458

2018
dbSNP: rs4918796
rs4918796
TCF7L2
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
dbSNP: rs12255372
rs12255372
TCF7L2
0.900 GeneticVariation GWASDB A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. 17460697

2007
dbSNP: rs12255372
rs12255372
TCF7L2
0.900 GeneticVariation GWASDB Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium. 17668382

2007
dbSNP: rs12255372
rs12255372
TCF7L2
0.900 GeneticVariation GWASDB A genome-wide association study identifies novel risk loci for type 2 diabetes. 17293876

2007
dbSNP: rs12255372
rs12255372
TCF7L2
0.900 GeneticVariation GWASDB Identification of susceptibility genes for complex diseases using pooling-based genome-wide association scans. 19184112

2009
dbSNP: rs12255372
rs12255372
TCF7L2
0.900 GeneticVariation GWASDB A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. 17463248

2007
dbSNP: rs7901695
rs7901695
TCF7L2
G 0.900 GeneticVariation GWASDB Genetic modifiers of cystic fibrosis-related diabetes. 23670970

2013