rs387907272
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Myd-88 L265P constitutive activating mutations are present in at least some cases of the diffuse large B-cell lymphoma form of vitreoretinal lymphoma.
|
25768255 |
2015 |
rs387907272
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Suppressing IL-10 significantly reduced STAT3 activation in both MYD88 WT and MYD88 L265P m</spa</span>n>utant lymphomas</span>.
|
30253331 |
2018 |
rs387907272
|
|
|
0.100 |
GeneticVariation |
BEFREE |
MYD88 L265P MUTATION DETECTION IN THE AQUEOUS HUMOR OF PATIENTS WITH VITREORETINAL LYMPHOMA.
|
30204732 |
2019 |
rs387907272
|
|
|
0.100 |
GeneticVariation |
BEFREE |
MYD88 L265P mutation has been reported in ∼90% of Waldenström's Macroglobulinemia (WM) patients and immunoglobulin M (IgM) monoclonal gammopathies of uncertain significance (MGUS), as well as in some cases of lymphoma and chronic lymphocytic leukemia.
|
24992174 |
2015 |
rs387907272
|
|
|
0.100 |
GeneticVariation |
BEFREE |
With clinical trials regarding their efficacy rapidly expanding to NHLs, we also discuss potential combinations of immune checkpoint inhibitors with the described targeted chemotherapies of L265P signaling networks, and/or with the above immunological approaches as potential ways of targeting MYD88-mutated lymphomas in the future.
|
30203262 |
2018 |
rs387907272
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Recurrent lymphoma-associated mutations, particularly Leu265Pro (L265P), within the MyD88 Toll/interleukin-1 receptor (TIR) domain sustain lymphoma cell survival due to constitutive nuclear factor κB signaling.
|
25359991 |
2014 |
rs387907272
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The MYD88 missense mutation c.794T>C, p.Leu265Pro, is found in patients with Waldenstörm's macroglobulinemia and lymphoma.
|
28042684 |
2017 |
rs387907272
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In order to evaluate whether the presence of the recently described MYD88 L265P mutation in patients with Waldenström's macroglobulinemia (WM) is contributory to SS-associated lymphomagenesis, a quantitative allele-specific PCR method was performed in peripheral blood derived from 90 SS patients as well as in minor salivary gland tissues derived from 12 primary SS patients with or without lymphoma.
|
24153350 |
2014 |
rs387907272
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Four cases of small lymphocyte-predominant benign PE from patients without history of lymphoma were examined and were all negative for MYD88 L265P mutation.
|
31556196 |
2019 |
rs387907272
|
|
|
0.100 |
GeneticVariation |
BEFREE |
HLA class I-restricted <i>MYD88</i> L265P-derived peptides as specific targets for lymphoma immunotherapy.
|
28405493 |
2017 |
rs387907272
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The discovery of MYD88 L265P mutations in the vast majority of LPLs has had a major impact on the study of these lymphomas.
|
26454445 |
2016 |
rs387907272
|
|
|
0.100 |
GeneticVariation |
BEFREE |
IGHV gene features and MYD88 L265P mutation separate the three marginal zone lymphoma entities and Waldenström macroglobulinemia/lymphoplasmacytic lymphomas.
|
22944768 |
2013 |