Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs587782386
rs587782386
MSH6 ; FBXO11
T 0.700 GeneticVariation CLINVAR Hereditary cancer-associated missense mutations in hMSH6 uncouple ATP hydrolysis from DNA mismatch binding. 18790734

2008
dbSNP: rs587782386
rs587782386
MSH6 ; FBXO11
T 0.700 GeneticVariation CLINVAR Involvement of hMSH6 in the development of hereditary and sporadic colorectal cancer revealed by immunostaining is based on germline mutations, but rarely on somatic inactivation. 11807791

2002
dbSNP: rs587782386
rs587782386
MSH6 ; FBXO11
T 0.700 GeneticVariation CLINVAR A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants. 22102614

2012
dbSNP: rs587782386
rs587782386
MSH6 ; FBXO11
T 0.700 GeneticVariation CLINVAR Structure of the human MutSalpha DNA lesion recognition complex. 17531815

2007
dbSNP: rs587782386
rs587782386
MSH6 ; FBXO11
T 0.700 GeneticVariation CLINVAR Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome. 25980754

2015