Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7799039
rs7799039
0.070 GeneticVariation BEFREE As regards, rs7799039 AA genotype showed significant higher leptin level than other genotypes in the same group with a non-significant difference in genotypes distribution between obese and controls. rs1137101 variant of leptin receptor and fasting leptin level are correlated with overweight and obesity in Saudi children. 29412799

2018

dbSNP: rs7799039
rs7799039
0.070 GeneticVariation BEFREE Therefore, we hypothesized that the LEP-rs7799039 and LEPR-rs1137101 SNPs are related to the risk of pre-pregnancy overweight/obesity (body mass index ≥25 kg/m<sup>2</sup>) as well as to excessive gestational weight gain (GWG) and high concentrations of leptin throughout pregnancy. 29241578

2017

dbSNP: rs7799039
rs7799039
0.070 GeneticVariation BEFREE Association of two obesity-related gene polymorphisms LEPG2548A rs7799039 and LEPRQ223R rs1137101 with the risk of breast cancer. 28938640

2017

dbSNP: rs7799039
rs7799039
0.070 GeneticVariation BEFREE The aim of this study was to investigate the association between overweight/obesity and polymorphisms in the LEP (rs7799039), LEP receptor (LEPR; rs1137101), and ADIPOQ genes (rs2241766, rs1501299) with the response to breast cancer treatment in Mexican women. 28416193

2017

dbSNP: rs7799039
rs7799039
0.070 GeneticVariation BEFREE Therefore, the present study aimed to evaluate the relationships among the gene polymorphisms ghrelin (GHRL-rs26802), ghrelin receptor (GHSR-rs572169), leptin (LEP-rs7799039), leptin receptor (LEPR-rs1137101) and fat mass and obesity-associated (FTO-rs9939609) and obesity. 26255942

2015

dbSNP: rs7799039
rs7799039
0.070 GeneticVariation BEFREE This study examined the association of a promoter polymorphism of the leptin gene (LEP), G-2548A (rs7799039), and two non-synonymous single nucleotide polymorphisms of the leptin receptor gene (LEPR), K109R (rs1137100) and Q223R (rs1137101), with body weight, body mass index (BMI) and obesity (BMI > or = 30) in Pacific Islanders. 20183928

2010

dbSNP: rs7799039
rs7799039
0.070 GeneticVariation BEFREE To examine the association of a common -2548G/A (rs7799039) promoter variant of the human leptin gene (LEP) with obesity or body mass index (BMI) and its associated phenotypes such as blood pressure variability and the prevalence of hypertension in a sample of the Tunisian population. 18923972

2008