|
rs72653706
|
|
A |
0.710 |
CausalMutation |
CLINVAR |
|
|
|
|
rs121908029
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs121913279
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs1554810066
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs1555517253
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs1568362252
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs199474657
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs28933696
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs63749796
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs63751241
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs72664204
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs72664207
|
|
C |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs754360599
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs7857345
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Conclusions:</b> The present research on the carotid artery stenosis patient cohort suggests the significant association between the rs4977574, rs7857345 and rs3798220 polymorphisms and carotid artery stenosis as well as between the rs4977574 and rs7857345 polymorphisms and atherogenic stroke.
|
31824394 |
2019 |
|
rs4636297
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Results:</b> The miR-126 gene rs4636297 polymorphism was associated with decreased small vessel stroke risk (GA vs. GG: odds ratio (OR) = 0.62, <i>p</i> = .015; GA + AA vs. GG: OR = 0.637, <i>p</i> = .018; A vs. G: OR = 0.696, <i>p</i> = .033).
|
30895838 |
2019 |
|
rs25487
|
|
|
0.030 |
GeneticVariation |
BEFREE |
<i>Results:</i> Polymorphism in <i>XRCC1</i> rs25487 was significantly associated with reduced ischemic stroke (IS) risk (dominant model: OR = 0.53, 95% CI = 0.36-0.79, <i>p</i> = 0.002), a milder initial stroke (dominant model: OR = 0.57, 95% CI = 0.33-0.98, <i>p</i> = 0.043), and also a better short-term recovery (dominant model: OR = 0.57, 95% CI = 0.35-0.92, <i>p</i> = 0.022).
|
27763529 |
2016 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
MTHFR C677T was prevalent among patients with recurrent stroke.
|
21824561 |
2011 |
|
rs28933698
|
|
|
0.010 |
GeneticVariation |
BEFREE |
C455R notch3 mutation in a Colombian CADASIL kindred with early onset of stroke.
|
12136071 |
2002 |
|
rs6007897
|
|
|
0.010 |
GeneticVariation |
BEFREE |
rs6007897 and rs4044210 in CELSR1 were associated with stroke risk individually (OR[95%CI]=1.43[1.13-1.81], p=0.003 and 1.38[1.09-1.74], p=0.007, respectively), and in combination as a haplotype.
|
21511255 |
2011 |
|
rs12425791
|
|
|
0.890 |
GeneticVariation |
BEFREE |
rs12425791 and rs11833579 were not associated with age of stroke onset (P = 0.786 and 0.340, respectively).
|
24995625 |
2014 |
|
rs104894845
|
|
|
0.020 |
GeneticVariation |
BEFREE |
No accumulation of neurologic events in family members of p.A143T patients with stroke/transient ischemic attacks was observed.
|
27142856 |
2016 |
|
rs76863441
|
|
|
0.020 |
GeneticVariation |
BEFREE |
V279F was not associated with major vascular events [7141 events; odds ratio (OR) = 0.98 per F variant, 95% confidence interval (CI) 0.90-1.06] or other vascular outcomes, including major coronary events (922 events; 0.96, 0.79-1.18) and stroke (5967 events; 1.00, 0.92-1.09).
|
27301456 |
2016 |
|
rs4986791
|
|
|
0.010 |
GeneticVariation |
BEFREE |
C1196T and C-260T, respectively, with ischemic stroke (n = 700), its subtypes and hemorrhagic stroke (n = 300) in a South Indian population from Telangana.
|
28963650 |
2017 |
|
rs28935197
|
|
|
0.010 |
GeneticVariation |
BEFREE |
N215S patients showed later symptom onset (males: p< 0.0001, females: p<0.03), later development of left ventricular hypertrophy (LVH) (median survival without LVH: 41 (non-N215S) vs. 64 (N215S) years, p< 0.0001), later development of proteinuria (median survival without proteinuria 43 (non-N215S) vs 71 years (N215S), p< 0.0001), later occurrence of cerebrovascular events (stroke/ Transient Ischaemic Attacks (TIA); median survival without stroke: 74 years (non-N215S) vs. not reached (N215S), p< 0.02), later decline in renal function to GFR <60 ml/min/1.73m2 (median survival: 56 (non-N215S) vs. 72 (N215S) years, p< 0.01), and greater overall survival (median survival 81 (N215S) vs. 66 (non-N215S) years, p< 0.0006).
|
29621274 |
2018 |
|
rs201118034
|
|
|
0.030 |
GeneticVariation |
BEFREE |
p.R544C <i>NOTCH3</i> mutation is underdiagnosed in stroke patients in Taiwan, especially in those with small vessel occlusion and sibling history of stroke.
|
30656190 |
2019 |