DisGeNET - a database of gene-disease associations

Essential Hypertension, C0085580

Variant: rs2960306 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs2960306

GRK4

0.020

GeneticVariation

BEFREE

Non-synonymous GRK4 variants, R65L, A142V and A486V, are associated with essential hypertension in diverse populations.

25732908

2016

dbSNP:

rs2960306

GRK4

0.020

GeneticVariation

BEFREE

To investigate the association between polymorphisms in the G protein-coupled receptor kinase 4 gene (GRK4) (R65L, A142V and A486V) and essential hypertension in northern Han Chinese, we conducted a case-control study consisting of 503 individuals with essential hypertension (HT) and 490 age-, gender-, and area-matched normotensive (NT) controls.

17044852

2006