|
rs486907
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In familial pancreatic cancer no association between Arg462Gln genotypes and pancreatic cancer risk was evident.
|
15981205 |
2005 |
|
rs74315364
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Glu265X mutation was identified in one (2.8%) familial and one (1.3%) sporadic pancreatic cancer case, but not in any of the controls.
|
15981205 |
2005 |
|
rs1799782
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We investigated the association between polymorphisms of MGMT (Leu(84)Phe and Ile(143)Val), APE1 (Asp(148)Glu), and XRCC1 (Arg(194)Trp and Arg(399)Gln) and risk of pancreatic cancer in a case-control study.
|
16844323 |
2006 |
|
rs25487
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We investigated the association between polymorphisms of MGMT (Leu(84)Phe and Ile(143)Val), APE1 (Asp(148)Glu), and XRCC1 (Arg(194)Trp and Arg(399)Gln) and risk of pancreatic cancer in a case-control study.
|
16844323 |
2006 |
|
rs111966833
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The SPINK1 mutations N34S and P55S occurred in five PC patients with a prevalence (4.1%) not significantly different from that observed (2.0%) in HC.
|
17072959 |
2006 |
|
rs2308321
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We investigated the association between polymorphisms of MGMT (Leu(84)Phe and Ile(143)Val), APE1 (Asp(148)Glu), and XRCC1 (Arg(194)Trp and Arg(399)Gln) and risk of pancreatic cancer in a case-control study.
|
16844323 |
2006 |
|
rs1130409
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated the association between polymorphisms of MGMT (Leu(84)Phe and Ile(143)Val), APE1 (Asp(148)Glu), and XRCC1 (Arg(194)Trp and Arg(399)Gln) and risk of pancreatic cancer in a case-control study.
|
16844323 |
2006 |
|
rs11554495
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our data suggest that the KRT8 alterations, Y54H and G62C, do not predispose patients to the development of pancreatitis or pancreatic cancer.
|
17039343 |
2006 |
|
rs12917
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated the association between polymorphisms of MGMT (Leu(84)Phe and Ile(143)Val), APE1 (Asp(148)Glu), and XRCC1 (Arg(194)Trp and Arg(399)Gln) and risk of pancreatic cancer in a case-control study.
|
16844323 |
2006 |
|
rs145733073
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The SPINK1 mutations N34S and P55S occurred in five PC patients with a prevalence (4.1%) not significantly different from that observed (2.0%) in HC.
|
17072959 |
2006 |
|
rs782095550
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The SPINK1 mutations N34S and P55S occurred in five PC patients with a prevalence (4.1%) not significantly different from that observed (2.0%) in HC.
|
17072959 |
2006 |
|
rs13181
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The XPD Asp312Asn and Lys751Gln polymorphisms, corresponding haplotype, and pancreatic cancer risk.
|
16458430 |
2007 |
|
rs1799782
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Yet only one polymorphism, XRCC1 Arg194Trp, appears to be involved in smoking-related cancers and in early onset pancreatic cancer.
|
17397816 |
2007 |
|
rs17107315
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Patients with the N34S mutation presented with earlier symptom onset and more dilatation of the main pancreatic duct, followed by more frequent surgical and/or endoscopic intervention and pancreatic cancer development than those without SPINK1 mutations.
|
17238043 |
2007 |
|
rs1049074086
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The role of S100P in the invasion of pancreatic cancer cells is mediated through cytoskeletal changes and regulation of cathepsin D.
|
17875703 |
2007 |
|
rs1176026649
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We estimated the contribution of the P239S variant, and surrounding sequence, to familial and early-onset pancreatic cancer.
|
17415588 |
2007 |
|
rs1339638227
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The purpose of this study was to investigate the association of the Aurora-A (T91A), and p16 (C540G and C580T) polymorphisms with age at diagnosis of pancreatic cancer.
|
17505013 |
2007 |
|
rs1799793
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We evaluated the association between the XPD exon 10 Asp(312)Asn and exon 23 Lys(751)Gln polymorphisms and the risk of pancreatic cancer in a hospital-based study of 344 patients and 386 controls frequency matched by age, gender, and race.
|
16458430 |
2007 |
|
rs1801275
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a subgroup of 149 cases and 135 controls, we studied the association of variants in IL-4 (C-589T, G3017T) and IL-4R alpha (Gln576Arg) with allergies and with risk of pancreatic cancer.
|
18031948 |
2007 |
|
rs1217691063
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We conducted a case-control study to assess the effect of alcohol on pancreatic cancer in conjunction with polymorphisms in one-carbon metabolism enzymes, methylenetetrahydrofolate reductase (MTHFR C677T), methionine synthase (MTR A2756G), methionine synthase reductase (MTRR A66G), and thymidylate synthase (TS) variable number of tandem repeat.
|
18843018 |
2008 |
|
rs121912651
|
|
|
0.020 |
GeneticVariation |
BEFREE |
To elucidate whether and how mutant p53 acquires its gain-of-function, mutant p53 is inducibly knocked down in the SW480 colon cancer cell line, which contains mutant p53(R273H/P309S), and the MIA PaCa-2 pancreatic cancer cell line, which contains mutant p53(R248W).
|
18701504 |
2008 |
|
rs4880
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Polymorphisms of the inflammatory pathway genes MPO -G463A and SOD2 Ala16Val are associated with elevated pancreatic cancer risk.
|
18205184 |
2008 |
|
rs111033565
|
|
|
0.010 |
GeneticVariation |
BEFREE |
HP patients with the p.R122H mutation have a 35% lifetime risk of developing pancreatic cancer, but the oncogenetic process remains unknown.
|
18946221 |
2008 |
|
rs121434592
|
|
|
0.010 |
GeneticVariation |
BEFREE |
AKT1 (E17K) mutation in pancreatic cancer.
|
18783292 |
2008 |
|
rs1555525012
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To elucidate whether and how mutant p53 acquires its gain-of-function, mutant p53 is inducibly knocked down in the SW480 colon cancer cell line, which contains mutant p53(R273H/P309S), and the MIA PaCa-2 pancreatic cancer cell line, which contains mutant p53(R248W).
|
18701504 |
2008 |