|
rs135745
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In MDR analysis, the combination of TIMELESS rs4630333 and CSNK1E rs135745 exhibited the most significant association with mood disorders in the two-locus model.
|
31323592 |
2019 |
|
rs1409851868
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Gln460Arg (rs2230912) polymorphism of the P2RX7 gene has been widely studied in mood disorders, however the results are still controversial.
|
30664971 |
2019 |
|
rs2271933
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An HCRTR1 gene variant (rs2271933 G > A) leading to amino acid substitution (Ile408Val) has been associated with migraine and mood disorders.
|
30742846 |
2019 |
|
rs4630333
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In MDR analysis, the combination of TIMELESS rs4630333 and CSNK1E rs135745 exhibited the most significant association with mood disorders in the two-locus model.
|
31323592 |
2019 |
|
rs6782011
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the present study, we assessed association between two GRM7 SNPs (rs6782011 and rs779867) and two neuropsychiatric disorders including attention deficit hyperactive disorder (ADHD) and mood disorders.
|
31170425 |
2019 |
|
rs779867
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the present study, we assessed association between two GRM7 SNPs (rs6782011 and rs779867) and two neuropsychiatric disorders including attention deficit hyperactive disorder (ADHD) and mood disorders.
|
31170425 |
2019 |
|
rs78809014
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Conclusions:</b> Although the exact mechanisms in the family remain to be elucidated, our data strongly indicate a probable role of the variant, rs78809014, in the regulatory process of the expression of MAPKAP1 and thus in the development of mood disorder in familial mood disorder.
|
30828345 |
2019 |
|
rs228682
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We also found that two other polymorphisms of PER3 gene, rs228682 and rs2640909, were associated with both AAD and family history of affective disorders.
|
30121446 |
2018 |
|
rs2640909
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We also found that two other polymorphisms of PER3 gene, rs228682 and rs2640909, were associated with both AAD and family history of affective disorders.
|
30121446 |
2018 |
|
rs6296
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The primary goal of this study was to determine the possible association between polymorphisms of genes encoding the serotonin receptors 5HT1A (rs6295), 5HT1B (rs6296), and 5HT2C (rs6318) and the presence of mood disorders in patients with TLE-HS.
|
29709878 |
2018 |
|
rs7713917
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The AA risk genotype of the Homer rs7713917 A>G SNP has been associated with mood disorders and suicide, and in healthy humans with brain function.
|
29079138 |
2018 |
|
rs10103191
|
|
|
0.010 |
GeneticVariation |
BEFREE |
When combining all samples, this SNP and multiple other SNPs at 2q11.2 (rs717454), 8q21.3 (rs10103191), and 11q13.2 (rs2167457) exhibited genome-wide significant association with major mood disorders.
|
29225345 |
2017 |
|
rs10748842
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Principally, the finding that NRG3 classes II and III are brain-specific isoforms predicted by rs10748842 risk genotype and are increased in mood disorders further implicates a molecular mechanism of psychiatric risk at the NRG3 locus and identifies a potential developmental role for NRG3 in bipolar disorder and major depression.
|
27771971 |
2017 |
|
rs10868235
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After logistic regression, independent risk factors for mood disorders in TLE were female sex, presence of concomitant anxiety disorders, and genetic variations in rs1867283 and rs10868235 NTRK2 variants.
|
28550723 |
2017 |
|
rs1867283
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After logistic regression, independent risk factors for mood disorders in TLE were female sex, presence of concomitant anxiety disorders, and genetic variations in rs1867283 and rs10868235 NTRK2 variants.
|
28550723 |
2017 |
|
rs2167457
|
|
|
0.010 |
GeneticVariation |
BEFREE |
When combining all samples, this SNP and multiple other SNPs at 2q11.2 (rs717454), 8q21.3 (rs10103191), and 11q13.2 (rs2167457) exhibited genome-wide significant association with major mood disorders.
|
29225345 |
2017 |
|
rs571720664
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The BDNF Val66Met polymorphism has been associated with sensitivity to stress and affective disorders.
|
28926000 |
2017 |
|
rs659366
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, there was a significant effect on occurrence of mood disorders in men with the minor alleles of -866G>A (rs659366) and Ala55Val (rs660339)) being associated with increasing odds of lifetime occurrence of mood disorders in a dose dependent manner.
|
28771482 |
2017 |
|
rs660339
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, there was a significant effect on occurrence of mood disorders in men with the minor alleles of -866G>A (rs659366) and Ala55Val (rs660339)) being associated with increasing odds of lifetime occurrence of mood disorders in a dose dependent manner.
|
28771482 |
2017 |
|
rs717454
|
|
|
0.010 |
GeneticVariation |
BEFREE |
When combining all samples, this SNP and multiple other SNPs at 2q11.2 (rs717454), 8q21.3 (rs10103191), and 11q13.2 (rs2167457) exhibited genome-wide significant association with major mood disorders.
|
29225345 |
2017 |
|
rs7597593
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Meta-analysis showed that rs1344706 and rs7597593 were both associated with major mood disorders as well as diagnosis of either BPD or MDD, although neither of the analyses achieved a genome-wide level of statistical significance.
|
27784192 |
2017 |
|
rs1789891
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The ADH gene cluster SNP rs1789891 and temperamental dimensions in patients with alcohol dependence and affective disorders.
|
26013422 |
2015 |
|
rs764165835
|
|
|
0.010 |
GeneticVariation |
BEFREE |
PON1 status (Q192R polymorphism and PON1 plasmatic activity), GSTM1, GSTT1, and STin.2 genotypes and alleles were assayed in 4 mutually exclusive study groups, i.e., comorbid mood disorder and TUD (n=95); TUD without mood disorders (n=90); mood disorders but no TUD (n=62); and controls (never-smokers without mood disorders; n=113).
|
25445355 |
2015 |
|
rs10994336
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Four of the most consistently replicated variants associated with mood disorder occur in genes important for synaptic function: ANK3 (rs10994336), BDNF (rs6265), CACNA1C (rs1006737), and DGKH (rs1170191).
|
24944871 |
2014 |
|
rs1170191
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Four of the most consistently replicated variants associated with mood disorder occur in genes important for synaptic function: ANK3 (rs10994336), BDNF (rs6265), CACNA1C (rs1006737), and DGKH (rs1170191).
|
24944871 |
2014 |