For the POAG group, C/C of R389G (C/G) in β1-ADR had a significantly lower diurnal mean IOP (p < 0.001), peak IOP (p = 0.010), trough IOP (p < 0.001), and larger IOP range (p = 0.047) than G carriers; C/C of R389G (C/G) in β1-ADR and G carriers had parallel diurnal IOP curves but significantly different diurnal IOP levels (p = 0.001); C/C of Q27E (C/G) in β2-ADR had a significantly higher diurnal mean IOP (p = 0.045) than G carriers; G/G of L84L (G/A) in β2-ADR had a significantly higher diurnal mean IOP (p = 0.044) than A carriers; C/C of R175R (C/A) in β2-ADR had a significantly higher diurnal mean IOP (p = 0.044) than A carriers; T/T of W64R (T/C) in β3-ADR had a significantly smaller IOP range (p = 0.001) than C carriers.