Gene: BRAF ×
Source: CURATED ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913351
rs121913351
BRAF
0.800 GeneticVariation UNIPROT Missense mutations of the BRAF gene in human lung adenocarcinoma. 12460919

2002
dbSNP: rs121913351
rs121913351
BRAF
0.800 GeneticVariation UNIPROT Guideline Recommendations for Testing of ALK Gene Rearrangement in Lung Cancer: A Proposal of the Korean Cardiopulmonary Pathology Study Group. 24627688

2014
dbSNP: rs121913351
rs121913351
BRAF
0.800 GeneticVariation UNIPROT Guideline Recommendations for EGFR Mutation Testing in Lung Cancer: Proposal of the Korean Cardiopulmonary Pathology Study Group. 23667368

2013
dbSNP: rs121913351
rs121913351
BRAF
0.800 GeneticVariation UNIPROT Non-small cell lung cancer and precision medicine: a model for the incorporation of genomic features into clinical trial design. 24846033

2014
dbSNP: rs121913351
rs121913351
BRAF
0.800 GeneticVariation UNIPROT Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology. 23562183

2013
dbSNP: rs121913351
rs121913351
BRAF
0.800 GeneticVariation UNIPROT Molecular testing for selection of patients with lung cancer for epidermal growth factor receptor and anaplastic lymphoma kinase tyrosine kinase inhibitors: American Society of Clinical Oncology endorsement of the College of American Pathologists/International Association for the study of lung cancer/association for molecular pathology guideline. 25311215

2014
dbSNP: rs121913366
rs121913366
BRAF
0.700 GeneticVariation UNIPROT Missense mutations of the BRAF gene in human lung adenocarcinoma. 12460919

2002
dbSNP: rs121913351
rs121913351
BRAF
A 0.800 CausalMutation CLINVAR Missense mutations of the BRAF gene in human lung adenocarcinoma. 12460919

2002
dbSNP: rs121913351
rs121913351
BRAF
A 0.800 CausalMutation CLINVAR BRAF and RAS mutations in human lung cancer and melanoma. 12460918

2002
dbSNP: rs121913351
rs121913351
BRAF
A 0.800 CausalMutation CLINVAR Kinase-impaired BRAF mutations in lung cancer confer sensitivity to dasatinib. 22649091

2012
dbSNP: rs121913351
rs121913351
BRAF
A 0.800 CausalMutation CLINVAR Clinical, pathologic, and biologic features associated with BRAF mutations in non-small cell lung cancer. 23833300

2013
dbSNP: rs121913351
rs121913351
BRAF
A 0.800 CausalMutation CLINVAR Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations. 21483012

2011
dbSNP: rs121913351
rs121913351
BRAF
A 0.800 CausalMutation CLINVAR Genetic predictors of MEK dependence in non-small cell lung cancer. 19010912

2008
dbSNP: rs121913351
rs121913351
BRAF
A 0.800 CausalMutation CLINVAR Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines. 19238210

2009
dbSNP: rs121913351
rs121913351
BRAF
A 0.800 CausalMutation CLINVAR Mutations of the BRAF gene in human cancer. 12068308

2002
dbSNP: rs387906660
rs387906660
BRAF
A 0.700 CausalMutation CLINVAR

dbSNP: rs1057519720
rs1057519720
BRAF
AA 0.700 CausalMutation CLINVAR Mutations of the BRAF gene in human cancer. 12068308

2002
dbSNP: rs1057519720
rs1057519720
BRAF
AA 0.700 CausalMutation CLINVAR Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations. 21483012

2011
dbSNP: rs1057519720
rs1057519720
BRAF
AA 0.700 CausalMutation CLINVAR Genetic predictors of MEK dependence in non-small cell lung cancer. 19010912

2008
dbSNP: rs1057519720
rs1057519720
BRAF
AA 0.700 CausalMutation CLINVAR Kinase-impaired BRAF mutations in lung cancer confer sensitivity to dasatinib. 22649091

2012
dbSNP: rs1057519720
rs1057519720
BRAF
AA 0.700 CausalMutation CLINVAR Lung adenocarcinoma with BRAF G469L mutation refractory to vemurafenib. 24035431

2013
dbSNP: rs1057519720
rs1057519720
BRAF
AA 0.700 CausalMutation CLINVAR Missense mutations of the BRAF gene in human lung adenocarcinoma. 12460919

2002
dbSNP: rs1057519720
rs1057519720
BRAF
AA 0.700 CausalMutation CLINVAR BRAF and RAS mutations in human lung cancer and melanoma. 12460918

2002
dbSNP: rs1057519720
rs1057519720
BRAF
AA 0.700 CausalMutation CLINVAR Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines. 19238210

2009
dbSNP: rs1057519720
rs1057519720
BRAF
AA 0.700 CausalMutation CLINVAR Clinical, pathologic, and biologic features associated with BRAF mutations in non-small cell lung cancer. 23833300

2013