Gene: FBXO11 ×
Source: CLINVAR ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1057517551
rs1057517551
MSH6 ; FBXO11
AT 0.700 GeneticVariation CLINVAR

dbSNP: rs1057517552
rs1057517552
MSH6 ; FBXO11
G 0.700 GeneticVariation CLINVAR

dbSNP: rs1553331659
rs1553331659
MSH6 ; FBXO11
GA 0.700 GeneticVariation CLINVAR

dbSNP: rs1553333093
rs1553333093
MSH6 ; FBXO11
C 0.700 GeneticVariation CLINVAR

dbSNP: rs1553333370
rs1553333370
MSH6 ; FBXO11
C 0.700 GeneticVariation CLINVAR

dbSNP: rs1553333753
rs1553333753
MSH6 ; FBXO11
ATTAT 0.700 GeneticVariation CLINVAR

dbSNP: rs1553410230
rs1553410230
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR

dbSNP: rs1553414029
rs1553414029
MSH6 ; FBXO11
T 0.700 GeneticVariation CLINVAR

dbSNP: rs1553414395
rs1553414395
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR

dbSNP: rs267608041
rs267608041
MSH6 ; FBXO11
TA 0.700 GeneticVariation CLINVAR

dbSNP: rs267608064
rs267608064
MSH6 ; FBXO11
G 0.700 GeneticVariation CLINVAR

dbSNP: rs267608098
rs267608098
MSH6 ; FBXO11
G 0.700 GeneticVariation CLINVAR Risks of Lynch syndrome cancers for MSH6 mutation carriers. 20028993

2010
dbSNP: rs267608098
rs267608098
MSH6 ; FBXO11
G 0.700 GeneticVariation CLINVAR Germ-line msh6 mutations in colorectal cancer families. 10537275

1999
dbSNP: rs267608122
rs267608122
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR Patients with an unexplained microsatellite instable tumour have a low risk of familial cancer. 17453009

2007
dbSNP: rs267608122
rs267608122
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312

2016
dbSNP: rs267608122
rs267608122
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR Risks of Lynch syndrome cancers for MSH6 mutation carriers. 20028993

2010
dbSNP: rs267608122
rs267608122
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR The contribution of deleterious germline mutations in BRCA1, BRCA2 and the mismatch repair genes to ovarian cancer in the population. 24728189

2014
dbSNP: rs267608122
rs267608122
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR Challenges in the identification of MSH6-associated colorectal cancer: rectal location, less typical histology, and a subset with retained mismatch repair function. 21836479

2011
dbSNP: rs267608122
rs267608122
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR Major contribution from recurrent alterations and MSH6 mutations in the Danish Lynch syndrome population. 18566915

2009
dbSNP: rs267608122
rs267608122
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR Familial endometrial cancer in female carriers of MSH6 germline mutations. 10508506

1999
dbSNP: rs267608122
rs267608122
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR Endometrial cancer in four sisters: report of a kindred with presumed cancer family syndrome. 8063241

1994
dbSNP: rs267608122
rs267608122
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database. 24362816

2014
dbSNP: rs267608122
rs267608122
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance. 15236168

2004
dbSNP: rs587779227
rs587779227
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database. 24362816

2014
dbSNP: rs587779227
rs587779227
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR A multifactorial likelihood model for MMR gene variant classification incorporating probabilities based on sequence bioinformatics and tumor characteristics: a report from the Colon Cancer Family Registry. 22949379

2013