DisGeNET - a database of gene-disease associations

Liver carcinoma, C2239176

Variant: rs2243115 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs2243115

IL12A ; IL12A-AS1

0.020

GeneticVariation

BEFREE

No relationships between the rs2243115 and rs3212227 SNPs and HCC risk were observed (all P > 0.05).

26631030

2016

dbSNP:

rs2243115

IL12A ; IL12A-AS1

0.020

GeneticVariation

BEFREE

To investigate the association between the potentially functional polymorphisms in IL12A and IL12B, HBV infection and risk of hepatocellular carcinoma in a Chinese population, we genotyped three polymorphisms, rs568408 (3'UTR G>A), rs2243115 (5'UTR T>G) in IL12A and rs3212227 (3'UTR A>C) in IL12B in a case-control study of 869 hepatocellular carcinoma (HCC) cases and 891 cancer-free controls.

20521253

2011