Obesity
|
0.730 |
Biomarker
|
disease |
MGD |
Carboxypeptidase E (CPE) deficiency in mice with the fat mutation have reduced stomach function.
|
9893169 |
1999 |
Obesity
|
0.730 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
The carboxypeptidase E knockout mouse exhibits endocrinological and behavioral deficits.
|
15358678 |
2004 |
Obesity
|
0.730 |
Biomarker
|
disease |
CTD_human |
Augmented pulmonary responses to acute ozone exposure in obese mice: roles of TNFR2 and IL-13.
|
23434795 |
2013 |
Obesity
|
0.730 |
GeneticVariation
|
disease |
BEFREE |
A mutation of carboxypeptidase E (CPE), an enzyme active in the processing and sorting of prohormones, causes obesity in the fat/fat mouse.
|
9207799 |
1997 |
Obesity
|
0.730 |
Biomarker
|
disease |
BEFREE |
The involvement of CPE and THBS1 in obesity allows us to suggest that the physiological processes controlled by these genes contribute to depot and gender-related differences in the metabolic complications of obesity.
|
12530526 |
2002 |
Obesity
|
0.730 |
Biomarker
|
disease |
MGD |
Fat (fat) and tubby (tub): two autosomal recessive mutations causing obesity syndromes in the mouse.
|
2250094 |
1991 |
Obesity
|
0.730 |
Biomarker
|
disease |
MGD |
Deficiencies in pro-thyrotropin-releasing hormone processing and abnormalities in thermoregulation in Cpefat/fat mice.
|
12270926 |
2002 |
Obesity
|
0.730 |
Biomarker
|
disease |
MGD |
Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity.
|
7663508 |
1995 |
Obesity
|
0.730 |
Biomarker
|
disease |
MGD |
Atherosclerosis in genetically obese mice: the mutants obese, diabetes, fat, tubby, and lethal yellow.
|
8177043 |
1994 |
Obesity
|
0.730 |
Biomarker
|
disease |
MGD |
Carboxypeptidase E is a regulated secretory pathway sorting receptor: genetic obliteration leads to endocrine disorders in Cpe(fat) mice.
|
9019408 |
1997 |
Obesity
|
0.730 |
GeneticVariation
|
disease |
BEFREE |
Thus, genetic variation in the CPE gene does not appear to play a major role in the pathogenesis of NIDDM or obesity in Japanese subjects.
|
9662053 |
1998 |
Obesity
|
0.730 |
Biomarker
|
disease |
MGD |
Intracellular misrouting and abnormal secretion of adrenocorticotropin and growth hormone in cpefat mice associated with a carboxypeptidase E mutation.
|
9144234 |
1997 |
Obesity
|
0.730 |
Biomarker
|
disease |
CTD_human |
The carboxypeptidase E knockout mouse exhibits endocrinological and behavioral deficits.
|
15358678 |
2004 |
Obesity
|
0.730 |
Biomarker
|
disease |
MGD |
Characterization of plasma lipids in genetically obese mice: the mutants obese, diabetes, fat, tubby, and lethal yellow.
|
8177042 |
1994 |