Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
LHGDN |
Angiotensinogen and ACE gene polymorphisms and risk of atrial fibrillation in the general population.
|
18496132 |
2008 |
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The results suggested an association between ACE insertion/deletion and AF risk.
|
20826259 |
2010 |
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Although activation of the renin-angiotensin-aldosterone system (RAAS) now appears to play a role in the pathophysiology of atrial fibrillation (AF), it remains to be determined if ACE genotype impacts response to conventional AAD therapy in patients with AF.
|
17556195 |
2007 |
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to investigate the role of the ACE I/D polymorphism in relation to the different clinical forms of AF, lone and secondary nonvalvular atrial fibrillation (NVAF).
|
17113662 |
2007 |
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The aim of the present study was to investigate the association of the angiotensin-converting enzyme 2350 G/A polymorphism with atrial fibrillation in Han Chinese patients with essential hypertension.
|
24270955 |
2013 |
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
We identified 21 SNPs and the angiotensin-converting enzyme insertion/deletion polymorphism that were reported to be associated with AF in the literature.
|
21056700 |
2011 |
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
We investigated the association between polymorphism in angiotensinogen (AGT) and angiotensin-converting enzyme gene and risk of acquired AF in a pair-matched case-control study conducted in Chinese Hans.
|
19932491 |
2010 |
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Polymorphisms of the angiotensin-converting enzyme and angiotensinogen gene in patients with atrial fibrillation.
|
21436211 |
2011 |
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
In patients with CHF, the presence of AF was significantly associated with certain ACE and eNOS genotypes.
|
16818212 |
2006 |
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
In a study in a Japanese population, it was reported that the angiotensin-converting enzyme insertion/deletion polymorphism was not associated with atrial fibrillation.
|
14631130 |
2003 |
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
LHGDN |
The purpose of this study was to investigate whether response to antiarrhythmic drug (AAD) therapy in patients with AF is modulated by the ACE I/D polymorphism.
|
17556195 |
2007 |
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Individuals with the ACE D/D genotype appear to be at higher risk of AF.
|
26041129 |
2015 |
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Our meta-analysis suggests that there is insufficient evidence to demonstrate an association between ACE I/D polymorphism and AF risk.
|
21076147 |
2011 |
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
We genotyped the insertion/ deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene in 138 HCM patients (26 with AF, 112 with sinus rhythm).
|
12166654 |
2002 |
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
It was recently suggested that the angiotensin-converting enzyme insertion/insertion genotype, which is considered to be protective against cardiovascular disease, was a significant risk factor for atrial fibrillation (AF) in patients with hypertrophic cardiomyopathy (HCM).
|
18037749 |
2007 |
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Angiotensin-converting enzyme and endothelial nitric oxide synthase polymorphisms in patients with atrial fibrillation.
|
12687832 |
2003 |
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Our study is to investigate whether treatment with ACE inhibitors (ACEIs) or angiotensin-receptor blockers (ARBs) could lower the risk of new AF in HCM.
|
29371376 |
2018 |
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Our study suggests that ACE I/D polymorphism is associated with AF and the DD genotype may be an independent predictive factor for AF in patients with hypertensive heart disease.
|
19117407 |
2009 |
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Genetic ACE I/D polymorphism and recurrence of atrial fibrillation after catheter ablation.
|
23876437 |
2013 |
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
LHGDN |
Our study suggests that ACE I/D polymorphism is associated with AF and the DD genotype may be an independent predictive factor for AF in patients with hypertensive heart disease.
|
19117407 |
2009 |
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Angiotensinogen a-20c genotype alone and in combination with ACE I/D genotype predicts an increased risk of atrial fibrillation.
|
18496132 |
2008 |
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The T allele carriers (TT + CT) had significantly increased risk of AF compared with the CC homozygotes (OR 1.94, 95% CI 1.20-3.14; adjusted P=0.006) in a logistic regression model after controlling age, left atrial dimension, and the use of angiotensin-converting enzyme inhibitors and/or angiotensin receptor blockers.
|
19665460 |
2009 |
Atrial Fibrillation
|
0.400 |
Biomarker
|
disease |
BEFREE |
Significant differences in the local conformations and kinetic properties of heart and lung ACEs demonstrate tissue specificity of ACE and provide a structural base for the development of mAbs able to distinguish heart and lung ACEs as a potential blood test for predicting atrial fibrillation risk.
|
28771512 |
2017 |
Atrial Fibrillation
|
0.400 |
Biomarker
|
disease |
BEFREE |
Age, smoking history, diabetes mellitus,hypertension frequency, angiotensin converting enzyme inhibitor-angiotensin receptor blocker use, CHA₂DS₂VASc and HAS-BLED scores, serum sST2 level, left atrium (LA) end-diastolic diameter, LA volume and LA volume index were related to AF recurrence.
|
30238709 |
2018 |
Atrial Fibrillation
|
0.400 |
Biomarker
|
disease |
BEFREE |
Renin-angiotensin system (RAS) inhibition via angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers may reduce the risk of developing atrial fibrillation (AF) in certain populations, but the evidence is conflicting.
|
27179719 |
2016 |