IFNG, interferon gamma, 3458

N. diseases: 1519; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007570
Disease: Celiac Disease
Celiac Disease
0.400 AlteredExpression disease BEFREE This study shows that activation of STAT-1 by IFN-gamma promotes T-bet in CD mucosa. 15247173 2004
CUI: C0007570
Disease: Celiac Disease
Celiac Disease
0.400 AlteredExpression disease BEFREE After culture with PT gliadin, an increase in IFN-gamma mRNA was observed in all nine patients with coeliac disease. 12477758 2003
CUI: C0007570
Disease: Celiac Disease
Celiac Disease
0.400 AlteredExpression disease BEFREE We found a significant positive correlation (p < 0.0001) between the expression of IFN-gamma and Bak mRNA in patients with untreated CD. 11908704 2002
CUI: C0007570
Disease: Celiac Disease
Celiac Disease
0.400 Biomarker disease BEFREE We conclude that isolated T cells spontaneously secreting IFN-gamma localize preferentially in the epithelium of patients with classical and refractory CD. 12472679 2002
CUI: C0007570
Disease: Celiac Disease
Celiac Disease
0.400 AlteredExpression disease BEFREE In DH patients, most of whom had no gut symptoms, IFN-gamma mRNA expression was significantly less than in isolated GSE patients with symptomatic gut disease. 10548367 1999
CUI: C0007570
Disease: Celiac Disease
Celiac Disease
0.400 Biomarker disease BEFREE Gluten induces an intestinal cytokine response strongly dominated by interferon gamma in patients with celiac disease. 9721152 1998
CUI: C0007570
Disease: Celiac Disease
Celiac Disease
0.400 AlteredExpression disease BEFREE Detection of interferon gamma mRNA in the mucosa of patients with coeliac disease by in situ hybridisation. 7926902 1994