BRCA2, BRCA2 DNA repair associated, 675

N. diseases: 656; N. variants: 3066
Disease: Hereditary Breast and Ovarian Cancer Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR Is physical working capacity determined by optimal magnesium concentration? 1295571 1993
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR Energetics of paraplegic walking. 1513140 1992
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR Regulation of phosphoenolpyruvate carboxylase from maize leaves by nitrate and alanine. 1859433 1991
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR A standardized technique for the placement of electrodes in the two heads of the lateral pterygoid muscle. 2073695 1990
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR Germline mutation of BRCA1 in Japanese breast cancer families. 7627958 1995
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR Identification of the breast cancer susceptibility gene BRCA2. 8524414 1996
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds. 8589730 1996
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR BRCA2 mutations in primary breast and ovarian cancers. 8640235 1996
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 GeneticVariation disease CLINVAR BRCA2 mutations in primary breast and ovarian cancers. 8640235 1996
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR A single BRCA2 mutation in male and female breast cancer families from Iceland with varied cancer phenotypes. 8673089 1996
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR Mutation analysis of the BRCA2 gene in 49 site-specific breast cancer families. 8673090 1996
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR BRCA2 germline mutations in male breast cancer cases and breast cancer families. 8673091 1996
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR Somatic and germline mutations of the BRCA2 gene in sporadic ovarian cancer. 8705994 1996
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR High prevalence of the 999del5 mutation in icelandic breast and ovarian cancer patients. 8706004 1996
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR A common mutation in BRCA2 that predisposes to a variety of cancers is found in both Jewish Ashkenazi and non-Jewish individuals. 8758903 1996
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR A polymorphic stop codon in BRCA2. 8896551 1996
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas. 8968085 1996
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene. 8988179 1997
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR Mutation analysis of BRCA1 and BRCA2 in a male breast cancer population. 9012404 1997
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR Mutations in BRCA1 and BRCA2 in breast cancer families: are there more breast cancer-susceptibility genes? 9042907 1997
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR The founder mutations 185delAG and 5382insC in BRCA1 and 6174delT in BRCA2 appear in 60% of ovarian cancer and 30% of early-onset breast cancer patients among Ashkenazi women. 9042909 1997
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR BRCA2 germline mutations in Japanese breast cancer families. 9133456 1997
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews. 9145676 1997
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR Differential contributions of BRCA1 and BRCA2 to early-onset breast cancer. 9145678 1997
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 CausalMutation disease CLINVAR BRCA2 in American families with four or more cases of breast or ovarian cancer: recurrent and novel mutations, variable expression, penetrance, and the possibility of families whose cancer is not attributable to BRCA1 or BRCA2. 9150150 1997