SNCA, synuclein alpha, 6622

N. diseases: 36; N. variants: 44
Source: CURATED ×
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs201106962
rs201106962 		0.851 0.080 4 89828156 missense variant A/C snv 8.0E-05 7.0E-05
CUI: C1868595
Disease: PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder)
PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder) 		0.700 1.000 7 1997 2015
dbSNP: rs1372518
rs1372518 		4 89836143 5 prime UTR variant A/C snv 0.77
CUI: C2985280
Disease: Blood Protein Measurement
Blood Protein Measurement 		0.700 1.000 1 2018 2018
dbSNP: rs2197120
rs2197120 		1.000 0.040 4 89808451 intron variant A/G snv 0.78
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		Nervous System Diseases 0.700 1.000 2 2011 2012
dbSNP: rs1372519
rs1372519 		1.000 0.040 4 89836158 5 prime UTR variant A/G snv 0.77
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		Nervous System Diseases 0.700 1.000 1 2011 2011
dbSNP: rs2572323
rs2572323 		1.000 0.040 4 89713401 intron variant A/G snv 0.75
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		Nervous System Diseases 0.700 1.000 1 2011 2011
dbSNP: rs2737002
rs2737002 		4 89832029 intron variant A/G snv 0.78
CUI: C2985280
Disease: Blood Protein Measurement
Blood Protein Measurement 		0.700 1.000 1 2018 2018
dbSNP: rs356180
rs356180 		1.000 0.040 4 89706976 intron variant A/G snv 0.77
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		Nervous System Diseases 0.700 1.000 1 2011 2011
dbSNP: rs8180209
rs8180209 		1.000 0.040 4 89723303 intron variant A/G snv 0.24
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		Nervous System Diseases 0.700 1.000 1 2017 2017
dbSNP: rs3857059
rs3857059 		1.000 0.040 4 89754087 intron variant A/G;T snv
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		Nervous System Diseases 0.710 1.000 3 2009 2016
dbSNP: rs10516845
rs10516845 		1.000 0.040 4 89763127 intron variant A/G;T snv
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		Nervous System Diseases 0.700 1.000 1 2011 2011
dbSNP: rs356221
rs356221 		1.000 0.040 4 89721313 intron variant A/T snv 0.44
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		Nervous System Diseases 0.710 1.000 2 2011 2013
dbSNP: rs7681440
rs7681440 		1.000 0.080 4 89835399 intron variant C/A;G snv
CUI: C0752347
Disease: Lewy Body Disease
Lewy Body Disease 		Nervous System Diseases; Mental Disorders 0.700 1.000 1 2018 2018
dbSNP: rs2583988
rs2583988 		0.925 0.080 4 89839677 non coding transcript exon variant C/A;T snv
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		Nervous System Diseases 0.720 1.000 1 2007 2012
dbSNP: rs104893878
rs104893878 		0.732 0.160 4 89835580 missense variant C/G snv
CUI: C1868595
Disease: PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder)
PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder) 		0.800 1.000 7 1997 2015
dbSNP: rs104893875
rs104893875 		0.742 0.120 4 89828170 missense variant C/T snv 4.0E-06
CUI: C1868595
Disease: PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder)
PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder) 		0.700 1.000 7 1997 2015
dbSNP: rs104893877
rs104893877 		0.614 0.360 4 89828149 missense variant C/T snv
CUI: C1868595
Disease: PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder)
PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder) 		0.800 1.000 7 1997 2015
dbSNP: rs356203
rs356203 		1.000 0.040 4 89744890 intron variant C/T snv 0.54
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		Nervous System Diseases 0.800 1.000 3 2011 2019
dbSNP: rs3822086
rs3822086 		1.000 0.040 4 89743643 intron variant C/T snv 0.24
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		Nervous System Diseases 0.730 1.000 2 2011 2019
dbSNP: rs10005233
rs10005233 		1.000 0.040 4 89822180 3 prime UTR variant C/T snv 0.58 0.59
CUI: C0003467
Disease: Anxiety
Anxiety 		Behavior and Behavior Mechanisms 0.700 1.000 1 2018 2018
dbSNP: rs104893875
rs104893875 		0.742 0.120 4 89828170 missense variant C/T snv 4.0E-06
CUI: C0752347
Disease: Lewy Body Disease
Lewy Body Disease 		Nervous System Diseases; Mental Disorders 0.860 1.000 1 2004 2019
dbSNP: rs168552
rs168552 		1.000 0.040 4 89721993 intron variant C/T snv 0.80
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		Nervous System Diseases 0.700 1.000 1 2011 2011
dbSNP: rs3775423
rs3775423 		1.000 0.040 4 89736340 intron variant C/T snv 0.24
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		Nervous System Diseases 0.700 1.000 1 2011 2011
dbSNP: rs3796661
rs3796661 		1.000 0.040 4 89766356 intron variant C/T snv 8.7E-02
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		Nervous System Diseases 0.700 1.000 1 2012 2012
dbSNP: rs3857053
rs3857053 		1.000 0.040 4 89724523 3 prime UTR variant C/T snv 0.24
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		Nervous System Diseases 0.700 1.000 1 2011 2011
dbSNP: rs104893877
rs104893877 		0.614 0.360 4 89828149 missense variant C/T snv
CUI: C0752347
Disease: Lewy Body Disease
Lewy Body Disease 		Nervous System Diseases; Mental Disorders 0.760 1.000 0 1998 2010