TPH2, tryptophan hydroxylase 2, 121278

N. diseases: 137; N. variants: 37
Disease: Major Depressive Disorder ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4570625
rs4570625
Entrez Id: 121278
Gene Symbol: TPH2
TPH2
CUI: C1269683
Disease:
Major Depressive Disorder 		0.030 GeneticVariation BEFREE They aimed to investigate the alterations in the cortical gyrification of the prefrontal cortex and anterior cingulate cortex and their association with the TPH2 rs4570625 polymorphism in patients with MDD. 27807918 2017
dbSNP: rs4570625
rs4570625
Entrez Id: 121278
Gene Symbol: TPH2
TPH2
CUI: C1269683
Disease:
Major Depressive Disorder 		0.030 GeneticVariation BEFREE Individuals carrying the T(-) genotype of rs4570625 (GG), T(-) genotype of rs11178997 (AA), or A(-) genotype of rs120074175 (GG) were susceptible to MD only when exposed to high-negative life events. 26386440 2015
dbSNP: rs4570625
rs4570625
Entrez Id: 121278
Gene Symbol: TPH2
TPH2
CUI: C1269683
Disease:
Major Depressive Disorder 		0.030 GeneticVariation BEFREE The synthesis of the data shown that two SNPs (rs4570625 and rs17110747) were associated with MDD using fixed effects models. 22693556 2012