IL4R, interleukin 4 receptor, 3566

N. diseases: 242; N. variants: 36
Disease: Asthma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1805015
rs1805015
Entrez Id: 3566
Gene Symbol: IL4R
IL4R
CUI: C0004096
Disease:
Asthma 		0.030 GeneticVariation BEFREE To evaluate whether polymorphisms of IL4R (rs1805015), IL13 (rs20541), IL17A (rs2275913) and GSTP1 (rs1695) genes are associated with rhinitis and/or asthma in adults of Portuguese ancestry. 27561723 2018
dbSNP: rs1805015
rs1805015
Entrez Id: 3566
Gene Symbol: IL4R
IL4R
CUI: C0004096
Disease:
Asthma 		0.030 GeneticVariation BEFREE Combining risk genotypes of IL13 Arg130Gln with IL4R Glu375Ala, and IL13 C-1111T with IL4R Ser478Pro yielded increased risks for asthma compared to their separate effects. 20484924 2010
dbSNP: rs1805015
rs1805015
Entrez Id: 3566
Gene Symbol: IL4R
IL4R
CUI: C0004096
Disease:
Asthma 		0.030 GeneticVariation BEFREE Genetic association analysis of polymorphisms revealed that six polymorphisms (c.899-2C>A, c.1199A>C, c.1242G>T, c.1291T>C, c.1299T>C, c.1507T>C) in the IL4R gene, three of which resulted in an amino-acid change, showed significant association with the risk of asthma (P = 0.00023). 17823973 2007