SNCA, synuclein alpha, 6622

N. diseases: 36; N. variants: 44
Disease: Parkinson Disease ×
Source: CURATED ×
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs356220
rs356220
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		T 0.850 GeneticVariation GWASDB SNCA_ rs356220 was associated with both Sporadic-PD (OR = 1.37, P = 1 × 10(-9)) and Familial-PD (OR = 1.40, P = 2 × 10(-5)). 24511991 2014
dbSNP: rs356220
rs356220
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		T 0.850 GeneticVariation GWASCAT SNCA_ rs356220 was associated with both Sporadic-PD (OR = 1.37, P = 1 × 10(-9)) and Familial-PD (OR = 1.40, P = 2 × 10(-5)). 24511991 2014
dbSNP: rs356220
rs356220
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		0.850 GeneticVariation GWASCAT Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2. 22451204 2012
dbSNP: rs356220
rs356220
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		0.850 GeneticVariation GWASDB Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2. 22451204 2012
dbSNP: rs356220
rs356220
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		0.850 GeneticVariation GWASDB Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. 22438815 2012
dbSNP: rs356220
rs356220
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		T 0.850 GeneticVariation GWASCAT Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease. 21738487 2011
dbSNP: rs356220
rs356220
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		T 0.850 GeneticVariation GWASDB Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population. 21084426 2011
dbSNP: rs356220
rs356220
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		A 0.850 GeneticVariation GWASCAT Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21. 21044948 2011
dbSNP: rs356220
rs356220
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		T 0.850 GeneticVariation GWASCAT Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population. 21084426 2011
dbSNP: rs356220
rs356220
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		T 0.850 GeneticVariation GWASDB Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease. 21738487 2011
dbSNP: rs356220
rs356220
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		A 0.850 GeneticVariation GWASDB Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21. 21044948 2011
dbSNP: rs356220
rs356220
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		T 0.850 GeneticVariation GWASCAT Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease. 20711177 2010
dbSNP: rs356220
rs356220
Entrez Id: 6622;105377329
Gene Symbol: SNCA;LOC105377329
SNCA;LOC105377329
CUI: C0030567
Disease:
Parkinson Disease 		T 0.850 GeneticVariation GWASDB Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease. 20711177 2010