TP53, tumor protein p53, 7157

N. diseases: 2494; N. variants: 527
Disease: Malignant Neoplasms ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs17880560
rs17880560
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0006826
Disease:
Malignant Neoplasms 		0.010 GeneticVariation BEFREE Statistical analyses stratified on family structure showed that cancer tended to occur ~15 years later in mutation carriers who also carried the variant alleles of two polymorphisms within predicted G4-forming regions, rs17878362 (TP53 PIN3, 16 bp duplication in intron 3; P = 0.082) and rs17880560 (6 bp duplication in 3' flanking region; P = 0.067). 24336192 2014