TP53, tumor protein p53, 7157

N. diseases: 2494; N. variants: 527
Disease: Neoplasms ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs730882002
rs730882002
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0027651
Disease:
Neoplasms 		0.020 GeneticVariation BEFREE NGS of the tumor showed an NRAS mutation (c.182A>G:p.Q61R) in 78%, a TP53 mutation (c.856G>A:p.E286K) in 60%, and a TERT gene mutation (1295250C>T) in 28% of the reads. 28973495 2017
dbSNP: rs730882002
rs730882002
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0027651
Disease:
Neoplasms 		0.020 GeneticVariation BEFREE The primary tumor and all the available metastases exhibited the same molecular oncogenic markers (namely, the RAS mutation p.Q61R and the telomerase promoter mutation C228T). 28781658 2017