Disease: Schizophrenia ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4765905
rs4765905
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		0.830 GeneticVariation BEFREE A history of suicide attempt was assessed in a sample of 1009 patients with BD, SCZ and related psychosis spectrum disorders, and associations with the joint genetic risk variants for BD and SCZ (rs2239547 (ITIH3/4-region), rs10994359 (ANK3) and rs4765905 (CACNA1C)) were investigated. 24461634 2014
dbSNP: rs2007044
rs2007044
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		0.710 GeneticVariation GWASCAT Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study. 31268507 2019
dbSNP: rs2007044
rs2007044
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		G 0.710 GeneticVariation GWASCAT Biological insights from 108 schizophrenia-associated genetic loci. 25056061 2014
dbSNP: rs10774037
rs10774037
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		A 0.700 GeneticVariation GWASCAT Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression. 30626913 2019
dbSNP: rs1006737
rs1006737
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		0.900 GeneticVariation BEFREE Both CACNA1C (rs1006737) and KCNH2 (rs3800779) were genotyped in 101 controls and 50 schizophrenia patients. 30607529 2019
dbSNP: rs1006737
rs1006737
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		0.900 GeneticVariation BEFREE CACNA1C gene polymorphism (rs1006737) is a susceptibility factor for both schizophrenia (SCZ) and bipolar disorder (BP). 22012475 2012
dbSNP: rs1006737
rs1006737
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		0.900 GeneticVariation BEFREE CACNA1C risk variant rs1006737 affects cortical white matter integrity in schizophrenia. 25470093 2014
dbSNP: rs1006737
rs1006737
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		0.900 GeneticVariation BEFREE CACNA1C-rs1006737 and ZNF804A-rs1344706 polymorphisms are among the most robustly associated with schizophrenia (SCZ) and bipolar disorder (BD), and recently with brain phenotypes. 30079586 2019
dbSNP: rs2007044
rs2007044
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		0.710 GeneticVariation GWASCAT Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. 29483656 2018
dbSNP: rs2239063
rs2239063
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		A 0.700 GeneticVariation GWASCAT Five novel loci associated with antipsychotic treatment response in patients with schizophrenia: a genome-wide association study. 29503163 2018
dbSNP: rs1006737
rs1006737
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		0.900 GeneticVariation BEFREE Further analysis of the haplotype rs1006737-rs4765905-rs882194 in CACNA1C showed significant associations with schizophrenia (corrected global p<0.005), and two haplotypes (ACC and ACT) in the block were significantly increased in the patients. 24275578 2014
dbSNP: rs4765905
rs4765905
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		0.830 GeneticVariation BEFREE Further analysis of the haplotype rs1006737-rs4765905-rs882194 in CACNA1C showed significant associations with schizophrenia (corrected global p<0.005), and two haplotypes (ACC and ACT) in the block were significantly increased in the patients. 24275578 2014
dbSNP: rs882194
rs882194
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		0.010 GeneticVariation BEFREE Further analysis of the haplotype rs1006737-rs4765905-rs882194 in CACNA1C showed significant associations with schizophrenia (corrected global p<0.005), and two haplotypes (ACC and ACT) in the block were significantly increased in the patients. 24275578 2014
dbSNP: rs10848635
rs10848635
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		0.010 GeneticVariation BEFREE Further, the rs10848635-rs1016388-rs1006737 haplotype was also associated with SCZ (P=0.03, simulate P=0.02). 26049408 2015
dbSNP: rs1016388
rs1016388
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		0.010 GeneticVariation BEFREE Further, the rs10848635-rs1016388-rs1006737 haplotype was also associated with SCZ (P=0.03, simulate P=0.02). 26049408 2015
dbSNP: rs1006737
rs1006737
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		A 0.900 GeneticVariation GWASDB Genome-wide association analysis identifies 13 new risk loci for schizophrenia. 23974872 2013
dbSNP: rs1006737
rs1006737
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		A 0.900 GeneticVariation GWASCAT Genome-wide association analysis identifies 13 new risk loci for schizophrenia. 23974872 2013
dbSNP: rs2159100
rs2159100
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		T 0.700 GeneticVariation GWASCAT Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia. 28991256 2017
dbSNP: rs758117
rs758117
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		C 0.700 GeneticVariation GWASCAT Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia. 28991256 2017
dbSNP: rs1006737
rs1006737
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		0.900 GeneticVariation BEFREE Genome-wide association studies have reported an association between the A-allele of rs1006737 within CACNA1C and affective disorders and schizophrenia. 22665259 2013
dbSNP: rs1024582
rs1024582
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		A 0.710 GeneticVariation GWASCAT Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect. 30285260 2019
dbSNP: rs2159100
rs2159100
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		T 0.700 GeneticVariation GWASCAT Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect. 30285260 2019
dbSNP: rs2239063
rs2239063
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		A 0.700 GeneticVariation GWASCAT Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect. 30285260 2019
dbSNP: rs758117
rs758117
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		C 0.700 GeneticVariation GWASCAT Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect. 30285260 2019
dbSNP: rs7972947
rs7972947
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0036341
Disease:
Schizophrenia 		0.700 GeneticVariation GWASDB Genome-wide association study identifies five new schizophrenia loci. 21926974 2011