rs113488022, BRAF

N. diseases: 490
Disease: ovarian neoplasm ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 CausalMutation CLINVAR Mutations of the BRAF gene in human cancer. 12068308 2002
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 CausalMutation CLINVAR Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial. 22608338 2012
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 CausalMutation CLINVAR Improved survival with vemurafenib in melanoma with BRAF V600E mutation. 21639808 2011
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 CausalMutation CLINVAR Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer--shifting the paradigm. 21683865 2011
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 GeneticVariation BEFREE In this study, we compared detection of the V600E mutation in serous ovarian tumors by VE1 immunostaining and by allele-specific polymerase chain reaction. 23089489 2013
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 CausalMutation CLINVAR KRAS or BRAF mutation status is a useful predictor of sensitivity to MEK inhibition in ovarian cancer. 19018267 2008
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 CausalMutation CLINVAR Inhibition of mutated, activated BRAF in metastatic melanoma. 20818844 2010
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 GeneticVariation BEFREE The presence of the BRAF V600E mutation in SB/LGS ovarian cancer was associated with early stage disease and improved prognosis. 22930283 2013
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 GeneticVariation BEFREE No BRAF V600E mutations were detected in nonserous epithelial ovarian tumors. 22820660 2013
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 CausalMutation CLINVAR Epidermal growth factor receptor blockers for the treatment of ovarian cancer. 21975775 2011
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 GeneticVariation BEFREE Sustained response to vemurafenib in a low grade serous ovarian cancer with a BRAF V600E mutation. 26490654 2015
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 GeneticVariation BEFREE One recurrent somatic mutation, p.V600E, is frequently found in several tumor types, such as melanoma, papillary thyroid carcinoma, colon cancer, and ovarian cancer. 20735442 2011